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Bis(benzimidazole) Complexes, Synthesis and Their Biological Properties: A Perspective
Benzimidazoles are a very well-known, broad group of compounds containing nitrogen atoms in their structure that can mimic properties of DNA bases. The compounds show not only biological activities but also are used for spectral and catalytic properties.
Zdeněk Šindelář, Pavel Kopel
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Benzimidazoles are important N-heteroaromatic compounds with various biological activities and pharmacological applications. Herein, we present the first iron-catalyzed selective synthesis of 1,2-disubstituted benzimidazoles via acceptorless ...
Ramachandra Reddy Putta +8 more
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In connection with our research program concerning development of novel effective benzimidazole-based anticancer candidates, herein we describe a new unexpected synthetic route to obtain a series of 2–((imidazole/benzimidazol2–yl)thio)1–arylethanones ...
Tarfah Al-Warhi +7 more
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The appearance of drug-resistant strains of Mycobacterium tuberculosis and the dramatic increase in infection rates worldwide evidences the urgency of developing new and effective compounds for treating tuberculosis. Benzimidazoles represent one possible
Rogelio Jiménez-Juárez +11 more
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Advances in the Synthesis of Ring-Fused Benzimidazoles and Imidazobenzimidazoles
This review article provides a perspective on the synthesis of alicyclic and heterocyclic ring-fused benzimidazoles, imidazo[4,5-f]benzimidazoles, and imidazo[5,4-f]benzimidazoles.
Martin Sweeney +3 more
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Cobamides are a family of enzyme cofactors that include vitamin B12 (cobalamin) and are produced solely by prokaryotes. Structural variability in the lower axial ligand has been observed in cobamides produced by diverse organisms. Of the three classes of
Terence S Crofts +3 more
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Synthesis of benzimidazole by mortar–pestle grinding method
An environmentally friendly and efficient protocol for the synthesis of benzimidazoles by mortar–pestle grinding technique in the presence of acetic acid as a catalyst is reported.
Peng Zhang +5 more
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Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines [PDF]
Three scaffolds of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines were synthesized via Ugi/de-protection/cyclization methodology. Benzimidazole forming ring closure was enabled under microwave irradiation in the presence of 10% TFA/DCE.
Zhigang, Xu +5 more
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This paper focused on the synthesis of phenylthiocarbamide-grafted graphene oxide (GO)-supported Cu complex (Cu-PTC@GO) as a highly efficient and recyclable catalyst synthesis by various analytical techniques such as TG, FT-IR, XRD, BET, N2 adsorption ...
Shahram Heidari +2 more
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The aim of the study is the investigation of the pharmacokinetic properties of the RU-1205 compound, with previously identified kappa-agonistic and analgesic effects, at a single oral administration, as well as comparison of the relationship between its ...
A. A. Spasov +8 more
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