Results 1 to 10 of about 40,476 (314)
A number of 2-substituted benzimidazoles has been prepared and the compounds were characterized by their physico-chemical and spectral properties. - Mutagenicity tests with two strains of Salmonella typhimurium revealed that on one hand the mutagenic ...
J.P. Seiler, H. Limacher
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Chemotherapy for the treatment of alveolar echinococcosis: Where are we? [PDF]
Alveolar echinococcosis (AE) is a severe liver disease due to infection with the Echinococcus multilocularis larval stage, called the metacestode. Management of AE is based on benzimidazole chemotherapy (albendazole or mebendazole), associated with ...
Autier Brice+2 more
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Bis(benzimidazole) Complexes, Synthesis and Their Biological Properties: A Perspective
Benzimidazoles are a very well-known, broad group of compounds containing nitrogen atoms in their structure that can mimic properties of DNA bases. The compounds show not only biological activities but also are used for spectral and catalytic properties.
Zdeněk Šindelář, Pavel Kopel
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Benzimidazoles are important N-heteroaromatic compounds with various biological activities and pharmacological applications. Herein, we present the first iron-catalyzed selective synthesis of 1,2-disubstituted benzimidazoles via acceptorless ...
Ramachandra Reddy Putta+8 more
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The appearance of drug-resistant strains of Mycobacterium tuberculosis and the dramatic increase in infection rates worldwide evidences the urgency of developing new and effective compounds for treating tuberculosis. Benzimidazoles represent one possible
Rogelio Jiménez-Juárez+11 more
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Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines [PDF]
AbstractA series of title compounds is synthesized by a strategy which involves Ugi four‐component condensation of the isonitrile (I) followed by TFA‐mediated deprotection and cyclization.
Gary S. Nichol+5 more
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In connection with our research program concerning development of novel effective benzimidazole-based anticancer candidates, herein we describe a new unexpected synthetic route to obtain a series of 2–((imidazole/benzimidazol2–yl)thio)1–arylethanones ...
Tarfah Al-Warhi+7 more
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Fischer, O., Hess, W.
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Dual Photochemistry of Benzimidazole
Monomers of benzimidazole trapped in an argon matrix at 15 K were characterized by vibrational spectroscopy and identified as 1H-tautomers exclusively. The photochemistry of matrix-isolated 1H-benzimidazole was induced by excitations with a frequency-tunable narrowband UV light and followed spectroscopically.
José P. L. Roque+3 more
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Advances in the Synthesis of Ring-Fused Benzimidazoles and Imidazobenzimidazoles
This review article provides a perspective on the synthesis of alicyclic and heterocyclic ring-fused benzimidazoles, imidazo[4,5-f]benzimidazoles, and imidazo[5,4-f]benzimidazoles.
Martin Sweeney+3 more
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