Degradation of lansoprazole and omeprazole in the aquatic environment [PDF]
Lansoprazole and omeprazole degrade in water leading to sulfides, benzimidazolones and a red complex material. Degradation is accelerated in acid medium and by solar simulator irradiation.
BRIGANTE M.+5 more
core +1 more source
α-Chymotrypsin-catalyzed synthesis of 2-substituted benzimidazole through retro-Claisen reaction
Benzimidazoles are important components of pharmaceutical compounds owing to their promising bioactivities. The green, safe, and efficient synthesis of benzimidazoles has always been one of the hot topics for chemical workers.
Lian-Sheng Liu+5 more
doaj +1 more source
In vitro anti-Leishmania activity of triclabendazole and its synergic effect with amphotericin B
IntroductionLeishmaniasis is a neglected tropical disease, with approximately 1 million new cases and 30,000 deaths reported every year worldwide. Given the lack of adequate medication for treating leishmaniasis, drug repositioning is essential to save ...
Beatriz Santana Borges+5 more
doaj +1 more source
Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds [PDF]
Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp.
Henriquez, Fiona L.+4 more
core +2 more sources
Hydrogen bonded interaction and synergistic effect on the corrosion protection properties of alkyl benzimidazoles and semicarbazide pair on mild steel in hydrochloric acid at 303, 308 and 313 K have been studied by polarization, electrochemical impedance
K. Ramya+3 more
doaj +1 more source
Multispecific resistance of sheep trichostrongylids in Austria
Anthelmintic overuse and failure to implement methods preventing the development and spread of anthelmintic resistance (AR) have led to an alarming increase of resistant ovine trichostrongylids worldwide.
Untersweg Florian+9 more
doaj +1 more source
Proton‐conducting polymers based on benzimidazoles and sulfonated benzimidazoles
AbstractA sulfonated derivative of polybenzimidazole is reported, and its properties are analyzed in comparison with related polybenzimidazole proton‐conducting materials. Poly(2,5‐benzimidazole), poly(m‐phenylenebenzobisimidazole), and poly[m‐(5‐sulfo)‐phenylenebenzobisimidazole] were prepared by condensation of the corresponding monomers in ...
Juan Antonio Asensio+2 more
openaire +3 more sources
New highlights of the syntheses of pyrrolo[1,2-a]quinoxalin-4-ones
The one-pot three-component reactions of 1-substituted benzimidazoles with ethyl bromoacetate and electron-deficient alkynes, in 1,2-epoxybutane, gave a variety of pyrrolo[1,2-a]quinoxalin-4-ones and pyrrolo[1,2-a]benzimidazoles.
Emilian Georgescu+6 more
doaj +1 more source
Solid Lipid Nanoparticles Enhancing the Leishmanicidal Activity of Delamanid
Leishmaniasis, a zoonotic parasitic disease transmitted by infected sandflies, impacts nearly 1 million people yearly and is endemic in many countries across Asia, Africa, the Americas, and the Mediterranean; despite this, it remains a neglected disease ...
Javier Santamaría-Aguirre+5 more
doaj +1 more source
In Vitro and In Vivo Effects of Tamoxifen against Larval Stage Echinococcus granulosus [PDF]
Cystic echinococcosis is a zoonotic infection caused by the larval stage of the cestode Echinococcus granulosus. Chemotherapy currently employs benzimidazoles; however, 40% of cases do not respond favorably.
Cumino, Andrea Carina+4 more
core +1 more source