Results 121 to 130 of about 43,525 (155)

Inhibition of BET proteins modulates amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation. [PDF]

Front Mol Neurosci
Matuszewska M, Wilkaniec A, Gąssowska-Dobrowolska M, Cieślik M, Olech-Kochańczyk G, Pałasz E, Gawinek E, Strawski M, Czapski GA.   +8 more
europepmc   +1 more source

PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.

Blood, 2021
Andrieu GP, Kohn M, Simonin M, Smith CL, Cieslak A, Dourthe MÉ, Charbonnier G, Graux C, Huguet F, Lhéritier V, Dombret H, Spicuglia S, Rousselot P, Boissel N, Asnafi V.   +14 more
europepmc   +1 more source

Inhibition of bromodomain and extra-terminal (BET) proteins with JQ1 exacerbates acetaminophen-induced hepatotoxicity by altering detoxification pathways and oxidative stress responses. [PDF]

Chem Biol Interact
Laddha AP, Seyednejad A, Donepudi AC, Goedken MJ, Manautou JE, Sartor GC.   +5 more
europepmc   +1 more source

Targeted inhibition of BET proteins in HPV16-positive head and neck squamous cell carcinoma reveals heterogeneous transcriptional responses. [PDF]

Front Oncol
Rao A, Stosic MS, Mohanty C, Suresh D, Wang AR, Lee DL, Nickel KP, Chandrashekar DS, Kimple RJ, Lambert PF, Kendziorski C, Rounge TB, Iyer G.   +12 more
europepmc   +1 more source

Correction: Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. [PDF]

J Biol Chem, 2020
Werner MT, Wang H, Hamagami N, Hsu SC, Yano JA, Stonestrom AJ, Behera V, Zhong Y, Mackay JP, Blobel GA.   +9 more
europepmc   +1 more source

Brd/BET Proteins Influence the Genome-Wide Localization of the Kaposi's Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Major Latency Proteins. [PDF]

Front Microbiol, 2020
Lotke R, Schneeweiß U, Pietrek M, Günther T, Grundhoff A, Weidner-Glunde M, Schulz TF.   +6 more
europepmc   +1 more source

Targeting BET Proteins With a PROTAC Molecule Elicits Potent Anticancer Activity in HCC Cells. [PDF]

Front Oncol, 2019
Zhang H, Li G, Zhang Y, Shi J, Yan B, Tang H, Chen S, Zhang J, Wen P, Wang Z, Pang C, Li J, Guo W, Zhang S.   +13 more
europepmc   +1 more source

Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma. [PDF]

Br J Cancer, 2020
Tiago M, Capparelli C, Erkes DA, Purwin TJ, Heilman SA, Berger AC, Davies MA, Aplin AE.   +7 more
europepmc   +1 more source

Testis specific gene expression drives disease progression and Rituximab resistance in lymphoma

EMBO Molecular Medicine, 2013
Stefan Knapp
doaj   +1 more source

Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity. [PDF]

Blood Adv, 2019
Carew JS, Espitia CM, Zhao W, Visconte V, Anwer F, Kelly KR, Nawrocki ST.   +6 more
europepmc   +1 more source