Results 91 to 100 of about 69,041 (263)

A Sequential Probability Ratio Test Using a Biased Coin Design

The Annals of Statistics, 1985
Consider a sequential probability ratio test comparing two treatments, where each subject receives only one of the treatments. Each subject's treatment assignment is determined by the flip of a biased coin, where the bias serves to balance the number of patients assigned to each treatment.
openaire   +2 more sources

The EC90 of remifentanil for blunting cardiovascular responses to head fixation for neurosurgery under total intravenous anesthesia with propofol and remifentanil based on bispectral index monitoring: estimation with the biased coin up-and-down sequential method

BMC Anesthesiology, 2017
Background Head fixation can induce hemodynamic instability. Remifentanil is commonly used with propofol for total intravenous anesthesia (TIVA) during neurosurgery.
Jung-Man Lee, Jae-Hyon Bahk, Young-Jin Lim, Jiwon Lee, Leerang Lim   +4 more
doaj   +1 more source

The Role of Actual and Purported Origin in e‐Commerce Wine Pricing: Evidence From Italian and French Names on Labels

Agribusiness, EarlyView.
ABSTRACT The origin of a product, if associated with good quality, can contribute to building a positive collective reputation, leading to a potential price premium. However, it is conceivable that a producer markets a product by evoking symbols, images, words, and values typical of places other than where it was designed or produced, creating a ...
Annalisa Caloffi, Amir Maghssudipour, Gianluca Stefani   +2 more
wiley   +1 more source

Animal‐Based Brands Taking the Plant‐Based Opportunity: A Tasting Experiment Exploring Consumer Acceptance of Plant‐Based Brand Extensions

Agribusiness, EarlyView.
ABSTRACT This study investigates how consumer taste and brand equity perceptions shape the acceptance of plant‐based milk products. Using a blind/informed tasting experiment, we evaluated consumers' willingness to buy (WTB) and taste perception of a plant‐based milk alternative produced by a traditional dairy brand, compared with competing plant‐based ...
Federico Parmiggiani, Mirta Casati, Elena Castellari, Fosca Vezzulli, Veronica Vitali, Milena Lambri, Claudio Soregaroli   +6 more
wiley   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Population stability: regulating size in the presence of an adversary

, 2018
We introduce a new coordination problem in distributed computing that we call the population stability problem. A system of agents each with limited memory and communication, as well as the ability to replicate and self-destruct, is subjected to attacks ...
Aspnes James, Berlekamp E. R, Cook Matthew, Di Luna Giuseppe Antonio, Dolev Shlomi, Gardner Martin, La Escalera G Martinez De, von Neumann John   +7 more
core   +1 more source

Generalized Efron's biased coin design and its theoretical properties

Journal of Applied Probability, 2016
AbstractIn clinical trials with two treatment arms, Efron's biased coin design, Efron (1971), sequentially assigns a patient to the underrepresented arm with probabilityp> ½. Under this design the proportion of patients in any arm converges to ½, and the convergence rate isn-1, as opposed ton-½under some other popular designs.
openaire   +3 more sources

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Large Language Model‐Based Chatbots in Higher Education

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci, Merve Eryilmaz, Ail K. Yetisen, Savas Tasoglu, Aydogan Ozcan   +4 more
wiley   +1 more source

What makes a phase transition? Analysis of the random satisfiability problem

, 2010
In the last 30 years it was found that many combinatorial systems undergo phase transitions. One of the most important examples of these can be found among the random k-satisfiability problems (often referred to as k-SAT), asking whether there exists an ...
Bollobás, Bollobás, Cheeseman, Chvátal, Davis, Elser, Garey, Gergely Palla, Hartmann, Katharina A. Zweig, Kirkpatrick, Krakala, Kropf, Marques-Silva, Marques-Silva, Mezárd, Mezárd, Mitchell, Monasson, Monasson, Monasson, Sinz, Stauffer, Tamás Vicsek   +23 more
core   +2 more sources