Results 71 to 80 of about 20,682 (267)

Doubly adaptive biased coin designs for balancing competing objectives in time-to-event trials [PDF]

open access: yesStatistics and Its Interface, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sverdlov, Oleksandr   +2 more
openaire   +2 more sources

Synergistic 3D Porous Architectures and Halogen Redox Chemistry for High‐Energy and High‐Power Microbatteries

open access: yesAdvanced Science, EarlyView.
3D porous Ni scaffolds with PANI cathode, Zn anode, and halogen redox chemistry synergistically enhance on‐chip microbattery performance by improving active material loading, Zn2+ diffusion, and charge‐transfer kinetics. The resulting 3D Zn//I2 microbatteries deliver high areal capacity, high energy and power density, and excellent cycling stability ...
Yijia Zhu   +6 more
wiley   +1 more source

Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor

open access: yes, 2016
Biased agonism describes the ability of distinct G protein-coupled receptor (GPCR) ligands to stabilise distinct receptor conformations leading to the activation of different cell signalling pathways that can deliver different physiologic outcomes.
Thompson, G.L.   +5 more
core   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

open access: yesAdvanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su   +13 more
wiley   +1 more source

Bias and loss: the two sides of a biased coin

open access: yes, 2012
The paper assesses biased-coin designs for sequential treatment allocation in clinical trials. Comparisons emphasise the importance of considering randomness, as well as treatment balance, which are calculated as bias and loss. In the numerical examples,
Anthony C. Atkinson   +1 more
core   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

open access: yesAdvanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando   +2 more
wiley   +1 more source

The minimum effective concentration (MEC90) of bupivacaine for an ultrasound-guided suprainguinal fascia iliaca compartment block for analgesia in knee surgery: a dose-finding study [PDF]

open access: yesKorean Journal of Anesthesiology
Background In recent years, the suprainguinal fascia iliaca compartment block (SFICB) has become more common in clinical practice. This assessor-blinded dose-finding study aimed to determine the minimum effective concentration (MEC90, MEC95) of ...
Caner Genc   +7 more
doaj   +1 more source

A doubly adaptive biased coin design.

open access: yes, 1991
A doubly adaptive biased coin design is formulated for the allocation of patients to treatments A and B in a clinical trial. The design is doubly adaptive in the sense that it takes account of the proportion of patients assigned to each treatment and the
Eisele, Jeffrey Robert
core  

Implications of Transient Negative Capacitance Effect in Ferroelectric Polarization Dynamics

open access: yesAdvanced Electronic Materials, EarlyView.
Transient voltage artifacts observed during ferroelectric switching are shown to originate from measurement circuitry rather than intrinsic negative capacitance. By correlating switching current, time scale, and series resistance, this work establishes practical design rules for reliable pulse‐switching experiments and circuit integration of ...
Marin Alexe
wiley   +1 more source

Design of the COIN study.

open access: yes, 2016
Design of the COIN study.
Gerard Dijkstra (208620)   +20 more
core   +1 more source

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