Results 1 to 10 of about 210,805 (138)

Minimum Effective Concentration of Ropivacaine for Ultrasound-Guided RISS Block in VATS: A Biased Coin Design Approach [PDF]

Drug Design, Development and Therapy
Ping Li,1,2 Zhongsai Yang,1,3 Long Zhang,4 Ruilan Wu,2 Manhua Zhu,2 Junran Xie1 1Department of Anesthesiology, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, Zhejiang Province, 310016, People’s Republic of China; 2Department ...
Li P, Yang Z, Zhang L, Wu R, Zhu M, Xie J   +5 more
doaj   +5 more sources

Effective dose of ciprofol combined with low-dose sufentanil for sedation of gastroscopy: a dose-finding study using a biased coin design [PDF]

BMC Anesthesiology
Objective This study aimed to determine the 90% effective dose of ciprofol combined with 5 µg of sufentanil for sedation during gastroscopy. Methods This was a double-blind, single-center dose-finding study.
Bingwei Hu, Ting Guan, Chenyuan Yu, Danfeng Wang, Qing Wang, Hongwei Wang   +5 more
doaj   +3 more sources

Determining the Minimum Effective Concentration of Ropivacaine in Epidural Anesthesia for Tolerable Pain in Transforaminal Percutaneous Endoscopic Lumbar Discectomy to Avoid Nerve Injury: A Double-Blind Study Using a Biased-Coin Design [PDF]

Drug Design, Development and Therapy, 2022
Bingwei Hu,1,2 Liang Li,2 Hongwei Wang,2 Tingting Ma,2 Zhimei Fu,2 Xianhui Kang,3 Zhiying Feng1 1Department of Pain, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Hu B, Li L, Wang H, Ma T, Fu Z, Kang X, Feng Z   +6 more
doaj   +3 more sources

Pharmacodynamics study of remimazolam besylate in anxious patients undergoing gastroscopy: a biased-coin design up-and-down sequential allocation trial [PDF]

BMC Anesthesiology
Background This study aimed to evaluate the impact of anxiety on the pharmacodynamics of remimazolam besylate in patients undergoing gastroscopy. Methods Patients undergoing gastroscopy were divided into two groups: an anxiety group (Self -rating Anxiety
Bao-Zhu Cha, Shuang-Yan Hu, Nian-Ping Chen, Jia-Fei Cao, Cheng Xu, Kai Qiu, Foquan Luo   +6 more
doaj   +3 more sources

The EC90 of remifentanil for inhibiting endotracheal intubation responses under anesthesia induction with ciprofol: study protocol for a dose-finding trial with the biased-coin design [PDF]

Trials
Background Tracheal intubation may cause significant hemodynamic responses. Many drugs have been shown to be effective in modifying these cardiovascular responses, including remifentanil, fentanyl, sufentanil, and alfentanil. However, the 90% effect-site
Jianing Guo, Fangsheng Xu, Luoyun Li, Zeru Zhang, Baichun Xing, Qin Fan, Zehua Wang, Chunyu Li   +7 more
doaj   +3 more sources

The 90% minimum effective volume and concentration of lidocaine for ultrasound-guided stellate ganglion blocks in adults: a biased-coin design, up-and-down sequential allocation trial [PDF]

Korean Journal of Anesthesiology
Background As ultrasound imaging technology matured, stellate ganglion blocks (SGBs) have become increasingly precise and safe, and their use in clinical practice has become widespread. However, the 90% minimum effective volume (MEV90) and concentration (
Shujun Sun, Qinghua Yin, Jiwei Shen, Yang Lv, Long Li, Zhangyan Mao, Yun Lin, Xiangdong Chen, Dong Yang   +8 more
doaj   +3 more sources

The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder: a biased coin design up-and-down sequential allocation trial [PDF]

BMC Anesthesiology
Background Chronic insomnia disorder is a common sleep disorder. Previous studies have reported increased demand for anesthetics in patients with chronic insomnia disorder.
Mengya Li, Guifeng Li, Qifang Li, Qing Cai   +3 more
doaj   +3 more sources

Determination of the ED90 and ED99 of Liposomal versus Conventional Bupivacaine for Ultrasound-Guided Stellate Ganglion Block: A Biased-Coin Design Study [PDF]

Drug Design, Development and Therapy
Litong Yang,1,* Junxiang Liu,2,* Yutong Yang,3 Haodong Zhao,4 Zhidong Fan,3 Guangfen Yin,3 Qinghang Xuan3 1Department of Anesthesiology, Xiangyun County People’s Hospital, Dali, Yunnan, People’s Republic of China; 2Department of ...
Yang L, Liu J, Yang Y, Zhao H, Fan Z, Yin G, Xuan Q   +6 more
doaj   +3 more sources

The Optimal Effective Concentration of Spinal Anesthesia for Interlaminar Endoscopic Lumbar Discectomy: An Approach Based on the Biased Coin Design [PDF]

Drug Design, Development and Therapy
Long Zhang,1,2,* Yu Zhang,1,2,* Ping Li,3 Bingwei Hu,4 Guanyi Liu,2,5 Miao Zhu,1,2 Liyong Yuan,1,2 Yaqing Xu1,2 1Department of Anesthesiology, Ningbo No.6 Hospital, Ningbo, Zhejiang, People’s Republic of China; 2Ningbo Clinical Research ...
Zhang L, Zhang Y, Li P, Hu B, Liu G, Zhu M, Yuan L, Xu Y   +7 more
doaj   +3 more sources

The 90% minimum effective concentration of ropivacaine for ultrasound‐guided interscalene brachial plexus block in children aged 1–10 years: A biased coin design up‐and‐down sequential allocation trial [PDF]

Pediatric Discovery
Ropivacaine is a commonly used local anesthetic for brachial plexus blocks in children, but the minimum effective dose of ropivacaine for interscalene brachial plexus blocks has not been reported.
Li Yang, Fei Yang, Yaqiong Tian, Ling Liu, Shangyingying Li, Tauseef Ahmad, Yuan Shi, Shengfen Tu   +7 more
doaj   +3 more sources