Conditioning Efron’s biased coin design to ensure final balance [PDF]
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Victoria P. Johnson
openaire +2 more sources
Robust quantum state engineering through coherent localization in biased-coin quantum walks [PDF]
We address the performance of a coin-biased quantum walk as a generator for non-classical position states of the walker. We exploit a phenomenon of coherent localization in the position space - resulting from the choice of small values of the coin ...
Helena Majury +4 more
doaj +6 more sources
The 90% Minimum Effective Dose of Oxycodone for Thoracoscopic Lobectomy in Elderly Patients: A Double-Blind Study Using a Biased-Coin Design. [PDF]
Purpose Postoperative pain significantly impairs recovery in elderly patients. Oxycodone is widely used in the postoperative period due to its favorable safety profile and low risk of respiratory depression.
Li S +6 more
europepmc +2 more sources
The 90% effective concentration of alfentanil combined with 0.075% ropivacaine for epidural labor analgesia: a single-center, prospective, double-blind sequential allocation biased-coin design. [PDF]
More literature studies have reported that alfentanil is safe and effective for labor analgesia. However, there is no unified consensus on the optimal dosage of alfentanil used for epidural analgesia.
Jia C +6 more
europepmc +2 more sources
Nuovi indicatori di sbilanciamento e prevedibilità nei disegni sequenziali randomizzati: confronti fra 'biased coin designs' diversi [PDF]
Efron's (1971) Biased Coin Design is a well-known randomization technique of sequential clinical trials for comparing two treatments in the absence of prognostic factors that helps neutralize selection bias while keeping the experiment fairly balanced ...
Alessandro Baldi Antognini +2 more
doaj +2 more sources
Determination of the ED90 of Remimazolam Bolus Dose for Preventing Emergence Delirium in Children with Sevoflurane Anesthesia: A Dose-Finding Study Using Biased-Coin Design Up-and-Down Sequential Method [PDF]
Purpose Emergence delirium (ED), a psychomotor agitation state, has a high incidence in children under sevoflurane anesthesia. Single-bolus administration of remimazolam can effectively reduce ED occurrence, similar to continuous infusion.
Xue B +5 more
europepmc +2 more sources
ED90 of intravenous remimazolam for alleviating preoperative anxiety in children: a prospective dose-finding study [PDF]
BackgroundChildren’s minds are immature, making them more susceptible to severe anxiety when separated from their parents before surgery. Alleviating preoperative anxiety in children is essential for providing comfort-oriented healthcare.
Xu-ming Zhu +5 more
doaj +2 more sources
Determination of the 90% effective dose of propofol combined with oliceridine or fentanyl for inhibiting the insertion response in upper gastrointestinal endoscopy: a dose-finding trial [PDF]
BackgroundPropofol combined with opioids is commonly used for procedural sedation, enhancing patient tolerance and reducing the incidence of adverse events. This study aimed to determine the 90% effective dose (ED90) of propofol combined with fentanyl or
Fangsheng Xu +10 more
doaj +2 more sources
Topical Airway Lidocaine Spray Reduces the 95% Effective Dose of Sufentanil for Blunting Hemodynamic Response to Tracheal Intubation in Elderly Patients: A Biased-Coin Up-and-Down Sequential Allocation Trial [PDF]
Xu Chen,1,* Jinjing Yang,2,* Kunyun Pan,1 Hao Wu,1 Sheng Wang,1 Wei Zhang,1 Chengwei Yang1 1Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology ...
Chen X +6 more
doaj +2 more sources
Minimum Effective Volume of 0.25% Ropivacaine for Ultrasound-Guided Superior Trunk Block with Dexmedetomidine Sedation in Shoulder Arthroscopy: A Biased Coin Up-and-Down Trial [PDF]
Kai Wang,1,2,* Shuhan Zhang,1,* Zhaoyu Lv,1,* Wei Chen,1 Yonghua Li1 1Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital), Shanghai, People’s Republic of China ...
Wang K, Zhang S, Lv Z, Chen W, Li Y
doaj +2 more sources

