Results 11 to 20 of about 1,463 (175)

Food Grade Synthesis of Hetero-Coupled Biflavones and 3D-Quantitative Structure–Activity Relationship (QSAR) Modeling of Antioxidant Activity [PDF]

Antioxidants
Biflavonoids are a unique subclass of dietary polyphenolic compounds known for their diverse bioactivities. Despite these benefits, these biflavonoids remain largely underexplored due to their limited natural availability and harsh conditions required ...
Hongling Zheng, Xin Yang, Qiuyu Zhang, Joanne Yi Hui Toy, Dejian Huang   +4 more
doaj   +2 more sources

3′-8″- Biflavones: A Review of Their Structural Diversity, Natural Occurrence, Role in Plants, Extraction and Identification [PDF]

Molecules
Dimeric forms of flavonoids, known as biflavonoids, are much less studied compared to monomeric forms. It is estimated that nearly 600 different natural biflavonoids have been described to date, containing various subtypes that can be subdivided ...
Dunja Šamec, Iva Jurčević Šangut, Erna Karalija, Bojan Šarkanj, Bruno Zelić, Anita Šalić   +5 more
doaj   +2 more sources

Biflavonoids can Potentially Inhibit Amyloid Beta Internalization to Mitigate Its Cytotoxic Events. [PDF]

Mol Nutr Food Res
Biflavonoids attenuate amyloid‐β (Aβ) induced cellular toxicity by inhibiting Aβ entry into cells. This blockade suppresses apoptosis‐related pathways, including caspase activation and nuclear lamin fragmentation, thereby promoting cellular protection and neuroprotective effects.
Haque MA, Hossain MS, Ramasamy VS, Park IS.   +3 more
europepmc   +2 more sources

Proceedings of Chemistry, Pharmacology, Pharmacokinetics and Synthesis of Biflavonoids

Molecules, 2021
Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms, bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally elucidated, and they can be classified into two groups of C-C and C-linear ...
Xinqian He, Fan Yang, Xin’an Huang
doaj   +1 more source

Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid [PDF]

Frontiers in Pharmacology, 2021
Amentoflavone is an active phenolic compound isolated fromSelaginella tamariscinaover 40 years. Amentoflavone has been extensively recorded as a molecule which displays multifunctional biological activities. Especially, amentoflavone involves in anti-cancer activity by mediating various signaling pathways such as extracellular signal-regulated kinase ...
Xifeng Xiong, Nan Tang, Xudong Lai, Jinli Zhang, Weilun Wen, Xiaojian Li, Aiguo Li, Yanhua Wu, Zhihe Liu   +8 more
openaire   +3 more sources

DNA topoisomerase inhibitors: biflavonoids from Ouratea species

Brazilian Journal of Medical and Biological Research, 2002
Topoisomerase inhibitors are agents with anticancer activity. 7"-O-Methyl-agathisflavone (I) and amentoflavone (II) are biflavonoids and were isolated from the Brazilian plants Ouratea hexasperma and O. semiserrata, respectively.
N.F. Grynberg, M.G. Carvalho, J.R. Velandia, M.C. Oliveira, I.C. Moreira, R. Braz- Filho, A. Echevarria   +6 more
doaj   +1 more source

Antiviral Activities of Biflavonoids

Planta Medica, 1999
Biflavonoids such as amentoflavone (1), agathisflavone (2), robustaflavone (3), hinokiflavone (4), volkensiflavone (5), rhusflavanone (7), succedaneflavanone (9), all isolated from Rhus succedanea and Garcinia multiflora, as well as their methyl ethers and acetates, volkensiflavone hexamethyl ether (6), rhusflavanone hexaacetate (8), and ...
Lin, Y. M., Flavin, M. T., Schure, R., Chen, F. C., Sidwell, R., Barnard, Dale L., Huffman, J. H., Kern, E. R.   +7 more
openaire   +3 more sources

In Vitro and In Silico Potential Inhibitory Effects of New Biflavonoids from Ochna rhizomatosa on HIV-1 Integrase and Plasmodium falciparum

Pharmaceutics, 2022
The aim of this study was to identify bioactive secondary metabolites from Ochna rhizomatosa with potential inhibitory effects against HIV and Plasmodium falciparum. A phytochemical study of O.
Angélique Nicolas Messi, Susan Lucia Bonnet, Brice Ayissi Owona, Anke Wilhelm, Eutrophe Le Doux Kamto, Joseph Thierry Ndongo, Xavier Siwe-Noundou, Madan Poka, Patrick H. Demana, Rui W. M. Krause, Joséphine Ngo Mbing, Dieudonné Emmanuel Pegnyemb, Christian G. Bochet   +12 more
doaj   +1 more source

Toxicodendron succedaneum (L.) Kuntze (Japanese wax tree): A review on its phytochemistry, pharmacology, and toxicity [PDF]

Pharmaceutical Sciences Asia, 2022
Toxicodendron succedaneum (L.) Kuntze (Anacardiaceae) is a deciduous tree widely distributed in South and Southeast Asia. The resin of T. succedaneum is used in decorating traditional handicrafts, and resinous latex is poisonous.
Shailendra S. Gurav, Charmaine Dias, Nilambari S. Gurav, Sameer J. Nadaf, Muniappan Ayyanar   +4 more
doaj   +1 more source

Toxoplasmocidal and Cytotoxic Activities Guided Isolation and Characterization of an Undescribed Bioflavonoid-di-C-glucoside from Cycas rumphii Miq. Cultivated in Egypt

Plants, 2022
Toxoplasmosis and cancer are serious worldwide diseases, and the available drugs cause serious side effects. Investigation for new alternative therapies from natural sources is now an increasing concern.
Hosam M. El-Seadawy, Kamilia A. Abo El-Seoud, Mona El-Aasr, Haytham O. Tawfik, Amany E. Ragab   +4 more
doaj   +1 more source