Results 31 to 40 of about 1,463 (175)

Lactate Dehydrogenase-Inhibitors Isolated from Ethyl Acetate Extract of Selaginella doederleinii by Using a Rapid Screening Method with Enzyme-Immobilized Magnetic Nanoparticles

Frontiers in Bioscience-Landmark, 2022
Background: Lactate dehydrogenase (LDH) is one of the important enzyme systems for glycolysis and gluconeogenesis. It can catalyze the reduction and oxidation reaction between propionic acid and L-lactic acid, which is usually overexpressed in cancer ...
Feng Zhang, Huiyun Li, Chao Liu, Kun Fang, Yongmei Jiang, Mingjiang Wu, Shiji Xiao, Lei Zhu, Jiaqi Yu, Shenge Li, Gang Wang   +10 more
doaj   +1 more source

Cytotoxic Biflavonoids from

Natural Product Communications, 2022
A new biflavonoid, (2″ S )-8″-C-methyl-2″,3″-dihydrorobustaflavone-4′-methyl ether ( 1 ) and 5 known robustaflavones ( 2 - 6 ) were isolated from the 70% EtOH extract of Selaginella braunii for the first time.
Xue-Feng Liu, Tong-Fei Fu, Jun-Song Wu, Bi-Chao Lu, Ping Zhang, He-Jing Liu   +5 more
doaj   +1 more source

Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley   +1 more source

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

Food Biomacromolecules, Volume 3, Issue 3, Page 515-531, September 2026.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li, Ziming Xu, Tian Zhao, Gongshuai Song, Danli Wang, Tinglan Yuan, Ling Li, Jinyan Gong   +7 more
wiley   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven, Mehmet Karadayı, Mustafa Abdullah Yilmaz, Osman Tugay, Oguz Cakir   +4 more
wiley   +1 more source

Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen) [PDF]

Chinese Medicine, 2010
Abstract Background Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). This study aims to identify the antiviral components of the active fraction.
Ye Wencai, Wang Yifei, Zhang Xiaoli, Huang Weihuan, Ooi Vincent EC, Chung Hau, Li Yaolan   +6 more
openaire   +3 more sources

Investigation of the Antibacterial Activity and Efflux Pump Inhibitory Effect of Cycas thouarsii R.Br. Extract against Klebsiella pneumoniae Clinical Isolates

Pharmaceuticals, 2021
The vast spread of multidrug-resistant bacteria has encouraged researchers to explore new antimicrobial compounds. This study aimed to investigate the phytochemistry and antibacterial activity of Cycas thouarsii R.Br.
Walaa A. Negm, Mona El-Aasr, Amal Abo Kamer, Engy Elekhnawy   +3 more
doaj   +1 more source

Synthesis of the Core Tetracycle of the Spirobiflavonoid Daphnodorin C

European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
Core spirotetracycle of daphnodorin C: Oxidative ring contraction of benzofuro[3,2‐b]chromenones affords novel 2,3′‐spirobi[benzofuran]diones, rather than the isomeric spiroketals. The first synthesis of the spirobi[benzofuran]dione core structure of the spirobiflavonoid daphnodorin C is described.
Lukas Heemann, Peter G. Jones, Thomas Lindel   +2 more
wiley   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Monoamine Oxidase Inhibitory Activity of Biflavonoids from Branches of (Clusiaceae)

Natural Product Communications, 2017
Garcinia gardneriana is chemically characterized by the presence of biflavonoids. Taking into account that flavonoids are able to inhibit monoamine oxidase (MAO) activity, in the present study, the chemical composition of the branches’ extract of the ...
Maria Angélica Recalde-Gil, Luiz Carlos Klein-Júnior, Carolina dos Santos Passos, Juliana Salton, Sérgio Augusto de Loreto Bordignon, Franco Delle Monace, Valdir Cechinel Filho, Amélia Teresinha Henriques   +7 more
doaj   +1 more source