Results 11 to 20 of about 8,243 (205)
Distribution of biglycan and decorin in rat dental tissue [PDF]
Brazilian Journal of Medical and Biological Research, 2003 Biglycan and decorin are small leucine-rich proteoglycans that play several biological and structural roles in different tissues and organs. Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in ...
D.M.H. Tenório +2 more
doaj +6 more sources
Biglycan in the skeleton [PDF]
Journal of Histochemistry & Cytochemistry, 2020 : Small leucine rich proteoglycans (SLRPs), including Biglycan, have key roles in many organ and tissue systems. The goal of this article is to review the function of Biglycan and other related SLRPs in mineralizing tissues of the skeleton. The review is
Shainer, Reut +5 more
core +4 more sources
Biglycan : a multivalent proteoglycan providing structure and signals [PDF]
Journal of Histochemistry & Cytochemistry, 2013 Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Schäfer, Liliana +2 more
core +4 more sources
The cleavage of biglycan by aggrecanases [PDF]
Osteoarthritis and Cartilage, 2006 SummaryObjectiveAggrecanase-1 [a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4] and aggrecanase-2 (ADAMTS-5) have been named for their ability to degrade the proteoglycan aggrecan.
Lee, E.R. +4 more
core +3 more sources
The Role of Decorin and Biglycan Signaling in Tumorigenesis [PDF]
Frontiers in Oncology, 2021 The complex and adaptive nature of malignant neoplasm constitute a major challenge for the development of effective anti-oncogenic therapies. Emerging evidence has uncovered the pivotal functions exerted by the small leucine-rich proteoglycans, decorin ...
Valentina Diehl +5 more
doaj +4 more sources
Borrelia burgdorferi Infection in Biglycan Knockout Mice [PDF]
The Journal of Infectious Diseases, 2019 Background: Borrelia burgdorferi sensu lato spirochetes (Borrelia) causing Lyme borreliosis are able to disseminate from the initial entry site to distant organs in the host.
Salo J. +7 more
core +5 more sources
Biologics: Targets & Therapy, 2012 Kristy Bolton1, David Segal1, Ken Walder1,21Metabolic Research Unit, School of Medicine, 2Institute for Technology, Research and Innovation, Deakin University, Waurn Ponds, Victoria, AustraliaAbstract: We have previously demonstrated that the small ...
Bolton K, Segal D, Walder K
doaj +1 more source
Decorin, biglycan and their endocytosis receptor in rat renal cortex [PDF]
Kidney International, 1998 Decorin, biglycan and their endocytosis receptor in rat renal cortex.BackgroundAmong the small proteoglycans, biglycan and decorin have been proposed to be potent modulators of TGF-β-mediated inflammatory kidney diseases.
Hausser, Heinz +7 more
core +3 more sources
Tumour necrosis factor-α interacts with biglycan and decorin [PDF]
FEBS Letters, 2002 Several interactions of cytokines with extracellular matrix molecules are mediated by proteoglycans, such as biglycan and decorin. Using surface plasmon resonance, we show for the first time that tumour necrosis factor-α (TNF-α) binds to both biglycan ...
Tufvesson, Ellen +3 more
core +3 more sources
The role of biglycan in the healthy and thoracic aneurysmal aorta
American Journal of Physiology-Cell Physiology, 2022 : The class I small leucine-rich proteoglycan biglycan is a crucial structural extracellular matrix component that interacts with a wide range of extracellular matrix molecules. In addition, biglycan is involved in sequestering growth factors such as TGF-
De Kinderen, Pauline +3 more
core +4 more sources