Results 11 to 20 of about 13,898 (220)
Biglycan regulates bone development and regeneration
Frontiers in Physiology, 2023 Endochondral bone development and regeneration relies on activation and proliferation of periosteum derived-cells (PDCs). Biglycan (Bgn), a small proteoglycan found in extracellular matrix, is known to be expressed in bone and cartilage, however little ...
Reut Shainer +11 more
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Distribution of biglycan and decorin in rat dental tissue [PDF]
Brazilian Journal of Medical and Biological Research, 2003 Biglycan and decorin are small leucine-rich proteoglycans that play several biological and structural roles in different tissues and organs. Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in ...
D.M.H. Tenório +2 more
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Biglycan in the Skeleton [PDF]
Journal of Histochemistry & Cytochemistry, 2020 Small leucine rich proteoglycans (SLRPs), including Biglycan, have key roles in many organ and tissue systems. The goal of this article is to review the function of Biglycan and other related SLRPs in mineralizing tissues of the skeleton. The review is divided into sections that include Biglycan’s role in structural biology, signaling, craniofacial ...
Kram, Vardit +5 more
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Breast cancer dataset with biomarker Biglycan
Data in Brief, 2023 تتكون مجموعة البيانات هذه من صور مجهرية للتعبير الكيميائي المناعي للبيغليكان (BGN) في أنسجة الثدي، مع السرطان وبدونه، باستخدام فقط تلطيخ 3-3'diaminobenzidine (DAB)، بعد معالجة الصور باستخدام مكون إضافي لإزالة الالتفاف اللوني، من Image J. تم الحصول على تعبير DAB الكيميائي المناعي للبيغليكان (BGN) باستخدام الجسم المضاد أحادي النسيلة (M01) (استنساخ 4E1 ...
Pedro Clarindo da Silva Neto +4 more
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Decorin knockdown is beneficial for aged tendons in the presence of biglycan expression
Matrix Biology Plus, 2022 Decorin and biglycan are two major small leucine-rich proteoglycans (SLRPs) present in the tendon extracellular matrix that facilitate collagen fibrillogenesis, tissue turnover, and cell signal transduction.
Zakary M. Beach +8 more
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Breast Cancer Research, 2021 Background Biglycan is a proteoglycan found in the extracellular matrix. We have previously shown that biglycan is secreted from tumor endothelial cells and induces tumor angiogenesis and metastasis.
Li Cong +8 more
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Journal of Histochemistry & Cytochemistry, 2012 Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule. Proteolytically released from the ECM, biglycan acts as a danger signal signifying tissue stress or injury.
Năstase, Mădălina-Viviana +2 more
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Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition. [PDF]
PLoS ONE, 2012 Cesarean birth rates are rising. Uterine dysfunction, the exact mechanism of which is unknown, is a common indication for Cesarean delivery. Biglycan and decorin are two small leucine-rich proteoglycans expressed in the extracellular matrix of ...
Zhiping Wu +5 more
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The cleavage of biglycan by aggrecanases [PDF]
Osteoarthritis and Cartilage, 2006 Aggrecanase-1 [a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4] and aggrecanase-2 (ADAMTS-5) have been named for their ability to degrade the proteoglycan aggrecan. While this may be the preferred substrate for these enzymes, they are also able to degrade other proteins.
Melching, L.I. +4 more
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European Journal of Histochemistry, 2020 The gene expression and protein synthesis of small leucine-rich proteoglycans (SLRPs), including decorin, biglycan, fibromodulin, and lumican, was analyzed in the context of the hypothesis that they are closely related to tooth formation.
Angammana Randilini +2 more
doaj +1 more source