Results 21 to 30 of about 7,104 (177)
Catabolism of aggrecan, decorin and biglycan in tendon [PDF]
Biochemical Journal, 2000 We have examined the catabolism of the proteoglycans aggrecan, decorin and biglycan in fresh tendon samples and in explant cultures of tissue from the tensional and compressed regions of young and mature bovine tendons. A panel of well-characterized antibodies that recognize glycosaminoglycan or protein (linear or neoepitope) sequences was used to ...
S G, Rees +5 more
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Breast cancer dataset with biomarker Biglycan
Data in Brief, 2023 تتكون مجموعة البيانات هذه من صور مجهرية للتعبير الكيميائي المناعي للبيغليكان (BGN) في أنسجة الثدي، مع السرطان وبدونه، باستخدام فقط تلطيخ 3-3'diaminobenzidine (DAB)، بعد معالجة الصور باستخدام مكون إضافي لإزالة الالتفاف اللوني، من Image J. تم الحصول على تعبير DAB الكيميائي المناعي للبيغليكان (BGN) باستخدام الجسم المضاد أحادي النسيلة (M01) (استنساخ 4E1 ...
Pedro Clarindo da Silva Neto +4 more
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Transcriptional Regulation of the Human Biglycan Gene [PDF]
Journal of Biological Chemistry, 1996 The small leucine-rich proteoglycan biglycan is involved in several physiological and pathophysiological processes through the ability of its core protein to interact with other extracellular matrix molecules and transforming growth factor-beta (TGF-beta).
H, Ungefroren, N B, Krull
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WISP-1 Binds to Decorin and Biglycan [PDF]
Journal of Biological Chemistry, 2001 Wnt-1-induced secreted protein 1 (WISP-1) is a member of the CCN (connective tissue growth factor, Cyr61, NOV) family of growth factors. Structural and experimental evidence suggests that CCN family member activities are modulated by their interaction with sulfated glycoconjugates.
L, Desnoyers, D, Arnott, D, Pennica
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Identification, characterization and expression analysis of biglycan in asian elephant (elephas maximus) [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 The aims of this study were to investigate the coding sequence and the deduced amino acid sequence of Asian elephant"s biglycan gene as well as its expression in different tissues and conditions using wound healing as a model.
Siriwadee CHOMDEJ +10 more
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Frontiers in Immunology, 2021 Primary Sjögren’s syndrome is an autoimmune disease that is predominantly seen in women. The disease is characterized by exocrine gland dysfunction in combination with serious systemic manifestations.
Jeremy Kiripolsky +7 more
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Expression and the Prognostic Value of Biglycan in Gastric Cancer
Computational and Mathematical Methods in Medicine, 2022 Background. Biglycan (BGN) is a family member of small leucine-rich repeat proteoglycans. High expression of BGN might enhance the invasion and metastasis in some types of tumors. Here, the prognostic significance of BGN was evaluated in gastric cancer. Material and Methods.
Sizhe Hu +3 more
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Science-Business eXchange, 2011 Tivorsan Pharmaceuticals is working with a Brown University team to optimize recombinant biglycan for delivery to patients with Duchenne muscular dystrophy. The work builds on the researchers' finding that the extracellular matrix glycoprotein decreases muscle pathology and improves muscle function in dystrophic mice.
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Cell Reports, 2020 Summary: Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate inflammation, here we investigate their role in adipose tissue inflammation in obesity. We find that adipose tissue versican and biglycan increase in obesity.
Chang Yeop Han +15 more
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Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer
Thoracic Cancer, 2021 Objectives In lung cancer, surgery remains the most curative treatment and limited resection is beneficial for patients with low cardiopulmonary function and low malignancy tumors.
Hirofumi Morimoto +9 more
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