Bile Salt Hydrolase Activity-Based Probes for Monitoring Gut Microbial Bile Acid Metabolism. [PDF]
Han L +5 more
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Partial liver resection alters the bile salt-FGF19 axis in patients with perihilar cholangiocarcinoma: Implications for liver regeneration. [PDF]
Koelfat KVK +13 more
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Microbially conjugated bile salts found in human bile activate the bile salt receptors TGR5 and FXR. [PDF]
Ay Ü +11 more
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Recombinant Bile Salt Hydrolase Enhances the Inhibition Efficiency of Taurodeoxycholic Acid against <i>Clostridium perfringens</i> Virulence. [PDF]
Alenezi T +7 more
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Cav-1 regulates the bile salt export pump on the canalicular membrane of hepatocytes by PKCα-associated signalling under cholesterol stimulation. [PDF]
Pang L, Cui M, Wu S, Kong J.
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▪ Abstract Bile salts are the major organic solutes in bile and undergo extensive enterohepatic circulation. Hepatocellular bile salt uptake is mediated predominantly by the Na+-taurocholate cotransport proteins Ntcp (rodents) and NTCP (humans) and by the Na+-independent organic anion-transporting polypeptides Oatp1, Oatp2, and Oatp4 (rodents) and ...
Meier, Peter J., Stieger, B.
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Bile Salt Metabolism:II. Bile Salts and Disease
Australian and New Zealand Journal of Medicine, 1977Alterations of bile salt metabolism have been shown in numerous diseases. Liver damage results in elevated serum bile salt concentrations which may be useful as a sensitive index of hepatocellular disease. Changes in the relative proportions of the individual bile salts in serum occur with cholestasis.
C B, Campbell, A E, Cowen
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Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
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Bile Salt Roles in Bile-Salt-Stimulated Lipase Activity
Journal of Pediatric Gastroenterology and Nutrition, 1986SummaryThe hydrolysis of 4‐nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5°C, and maximum activity was observed for both substrates at 1 mmole/ dm−3 bile salt.
C J, O'Connor, P, Walde, R G, Wallace
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