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Partial liver resection alters the bile salt-FGF19 axis in patients with perihilar cholangiocarcinoma: Implications for liver regeneration. [PDF]

open access: yesHepatol Commun
Koelfat KVK   +13 more
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Microbially conjugated bile salts found in human bile activate the bile salt receptors TGR5 and FXR. [PDF]

open access: yesHepatol Commun
Ay Ü   +11 more
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Bile Salt Transporters

Annual Review of Physiology, 2002
▪ Abstract  Bile salts are the major organic solutes in bile and undergo extensive enterohepatic circulation. Hepatocellular bile salt uptake is mediated predominantly by the Na+-taurocholate cotransport proteins Ntcp (rodents) and NTCP (humans) and by the Na+-independent organic anion-transporting polypeptides Oatp1, Oatp2, and Oatp4 (rodents) and ...
Meier, Peter J., Stieger, B.
openaire   +4 more sources

Bile Salt Metabolism:II. Bile Salts and Disease

Australian and New Zealand Journal of Medicine, 1977
Alterations of bile salt metabolism have been shown in numerous diseases. Liver damage results in elevated serum bile salt concentrations which may be useful as a sensitive index of hepatocellular disease. Changes in the relative proportions of the individual bile salts in serum occur with cholestasis.
C B, Campbell, A E, Cowen
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Bile salt diarrhea

Current Gastroenterology Reports, 2005
Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
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Bile Salt Roles in Bile-Salt-Stimulated Lipase Activity

Journal of Pediatric Gastroenterology and Nutrition, 1986
SummaryThe hydrolysis of 4‐nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5°C, and maximum activity was observed for both substrates at 1 mmole/ dm−3 bile salt.
C J, O'Connor, P, Walde, R G, Wallace
openaire   +2 more sources

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