Results 151 to 160 of about 71,391 (320)

Sacrificial strategy towards the formation of vascular‐like networks in volumetric tissue constructs

open access: yesBMEMat, EarlyView.
This mini‐review highlights the latest progress in the sacrificial template‐enabled creation of patent vascular‐like networks, which can be incorporated into volumetric tissue constructs. Such microchannel networks can provide an immediate supply of nutrition and O2 to those cells residing next to the channels.
Christian Buckley   +5 more
wiley   +1 more source

Designing next‐generation immune cell therapies with nanomaterials

open access: yesBMEMat, EarlyView.
Nanomaterials are transforming immune cellular therapies (ICT) by addressing challenges like tumor accessibility and lengthy manufacturing. This perspective highlights innovations such as magnetic nanoparticles for target identification, lipid nanoparticles for T cell stimulation, and nanoparticle‐mediated gene cytokine delivery. These advances promise
Kangfu Chen, Wenhan Wang, Zongjie Wang
wiley   +1 more source

Harnessing cell aggregates for enhanced adeno‐associated virus manufacturing: Cultivation strategies and scale‐up considerations

open access: yesBiotechnology Progress, EarlyView.
Abstract The possibility to produce recombinant adeno‐associated virus (rAAV) by adherent HEK293T cells was studied in a stirred tank bioreactor (STR) culture of cell aggregates. A proof‐of‐concept of rAAV production was successfully demonstrated in a process where single cells were first expanded, then cell aggregates were formed by dilution into a ...
Brian Ladd   +2 more
wiley   +1 more source

Characterization of biodegradable food packaging films prepared with polyamide 4: Influence of molecular weight and environmental humidity

open access: yesFood Bioengineering, Volume 1, Issue 3-4, Page 276-288, December 2022., 2022
Colorless and translucent polyamide 4 (PA4) films, which are both bio‐based and biodegradable, were prepared by the solution casting method in a dual‐solvent system. The physical properties of single PA4 films were originally characterized, and the effects of molecular weight and environmental humidity on PA4 were investigated. Abstract The development
Di Zhang   +6 more
wiley   +1 more source

Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction

open access: yesNature Communications
Identifying and characterizing virulence proteins secreted by Gram-negative bacteria are fundamental for deciphering microbial pathogenicity as well as aiding the development of therapeutic strategies.
Yue Peng   +5 more
doaj   +1 more source

Characterization of large transgene integrations in Chinese hamster ovary cells using a bioengineered mammalian transposase

open access: yesBiotechnology Progress, EarlyView.
Abstract We present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA.
Nicolas Marx   +10 more
wiley   +1 more source

Lactiplantibacillus plantarum X7022 ameliorates loperamide‐induced constipation and modulates gut microbiota in mice

open access: yesFood Bioengineering, Volume 1, Issue 3-4, Page 252-263, December 2022., 2022
Lactiplantibacillus plantarum X7022 is a novel strain isolated from the traditional fermented stinky tofu brine. L. plantarum X7022 could alleviate constipation by improving defection indices. L. plantarum X7022 regulated gut microbiota dysbiosis in the two different constipation models.
Xingye Chen   +5 more
wiley   +1 more source

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