A study on the convergence of observer-based kinetics estimators in stirred tank bioreactors [PDF]
Rui Oliveira+3 more
openalex +1 more source
Abstract One strategy to enhance the production of biological therapeutics is using transient perfusion in the preculture (N‐1 stage) to seed the production culture (N stage) at ultra‐high cell densities (>10 x 106 viable cells/mL). This very high seeding density improves cell culture performance by shortening the timeline and/or achieving higher final
Lucas Lemire+5 more
wiley +1 more source
Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state?
Our proposed model of spheroid isolation from liposuction fat. The tissue disintegration releases the pre‐existing spheroids as intact structures. This could be the ideal technique to culture cells in suspension because it avoids a preliminary adhesion isolation step and thus an upstream cell selection.
Anna Barbara Di Stefano+5 more
wiley +1 more source
Characterizing the effect of impeller design in plant cell fermentations using CFD modeling. [PDF]
Manickavasagam VM+3 more
europepmc +1 more source
Development of the Delft inclined plate (DIP) bioreactor
Gus Van Weert, Peter Kroes
openalex +2 more sources
Bioreactor for continuous synthesis of compactin by Penicillium cyclopium [PDF]
W. A. Bazaraa, M. K. Hamdy, R. Toledo
openalex +1 more source
Continuous purification of a parvovirus using two aqueous two‐phase extraction steps
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold+11 more
wiley +1 more source
Huperzine A Production and Acetylcholinesterase Inhibition by <i>Phlegmariurus taxifolius</i> Cell Suspension Culture: A Comparative Study in Flasks and an Airlift Bioreactor. [PDF]
Pérez Aguilar RDC+9 more
europepmc +1 more source
Biological conversion of synthesis gas. Topical report: Bioreactor studies
Rahul Basu+3 more
openalex +2 more sources
Ethanol production by immobilized whole cells ofZymomonas mobilis in a continuous flow expanded bed bioreactor and a continuous flow stirred tank bioreactor [PDF]
S. Siva Kesava, T. Panda
openalex +1 more source