Results 31 to 40 of about 72,831 (298)

Real-time and on-line monitoring of ethanol fermentation process by viable cell sensor and electronic nose

Bioresources and Bioprocessing, 2021
In this study, introduction of a viable cell sensor and electronic nose into ethanol fermentation was investigated, which could be used in real-time and on-line monitoring of the amount of living cells and product content, respectively.
Yao Feng, Xiwei Tian, Yang Chen, Zeyu Wang, Jianye Xia, Jiangchao Qian, Yingping Zhuang, Ju Chu   +7 more
doaj   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

Modulation of acetate utilization in Komagataella phaffii by metabolic engineering of tolerance and metabolism

Biotechnology for Biofuels, 2019
Background Acetate, an economical industrial chemical, which is also the precursor of acetyl-CoA, could serve as an alternative substrate for biomanufacturing.
Qin Xu, Chenxiao Bai, Yiqi Liu, Lili Song, Lin Tian, Yunfeng Yan, Jinfeng Zhou, Xiangshan Zhou, Yuanxing Zhang, Menghao Cai   +9 more
doaj   +1 more source

Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation

Microbial Cell Factories, 2020
Background Glucoamylase is one of the most industrially applied enzymes, produced by Aspergillus species, like Aspergillus niger. Compared to the traditional ways of process optimization, the metabolic engineering strategies to improve glucoamylase ...
Weiqiang Cao, Guan Wang, Hongzhong Lu, Liming Ouyang, Ju Chu, Yufei Sui, Yingping Zhuang   +6 more
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

N,N-dimethylformamide induces cellulase production in the filamentous fungus Trichoderma reesei

Biotechnology for Biofuels, 2019
Background The filamentous fungus Trichoderma reesei produces cellulase enzymes that are widely studied for lignocellulose bioconversion to biofuel.
Yumeng Chen, Chuan Wu, Yaling Shen, Yushu Ma, Dongzhi Wei, Wei Wang   +5 more
doaj   +1 more source

Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

Bioresources and Bioprocessing, 2022
Background β-Nicotinamide mononucleotide (NMN) is the direct precursor of nicotinamide coenzymes such as NAD+ and NADP+, which are widely applied in industrial biocatalysis especially involving cofactor-dependent oxidoreductases.
Xiao-Long Qian, Yi-Si Dai, Chun-Xiu Li, Jiang Pan, Jian-He Xu, Bozhong Mu   +5 more
doaj   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella

BMC Microbiology, 2017
Background Conjugation is a major type of horizontal transmission of genes that involves transfer of a plasmid into a recipient using specific conjugation machinery, which results in an extended spectrum of bacterial antibiotics resistance.
Yang Liu, Yanan Gao, Xiaohong Liu, Qin Liu, Yuanxing Zhang, Qiyao Wang, Jingfan Xiao   +6 more
doaj   +1 more source

Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1

mAbs, 2023
Antibody-based immune checkpoint blockade (ICB)-based therapeutics have become effective clinical applications for cancers. Applications of monoclonal antibodies (mAbs) to de-activate the PD-1-PD-L1 pathway could effectively reverse the phenotype of ...
Mengzhen Jiang, Man Liu, Guodi Liu, Jiawen Ma, Lixin Zhang, Shenlin Wang   +5 more
doaj   +1 more source