Mechanochemistry in Organic Synthesis: An Italian Journey through Innovations
European Journal of Organic Chemistry, Volume 27, Issue 30, August 12, 2024.The contribution of Italy to the development of mechanochemistry dates back to 1988 with the first studies on metal alloys. With the progress of time, it has flourished not only in the field of organic chemistry, but also in other scientific fields due to the enormous interest of Italian researchers in the various advantages brought by this technique ...
Francesco Basoccu +2 more
wiley +1 more source
Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine
Molecules, 2014 In previous works we showed that oral administration of caulerpine, a bisindole alkaloid isolated from algae of the genus Caulerpa, produced antinociception when assessed in chemical and thermal models of nociception.
Luiz Henrique Agra Cavalcante-Silva +11 more
doaj +1 more source
Molecular Networking‐Guided Discovery of Kyonggic Acids in Massilia spp.
European Journal of Organic Chemistry, Volume 27, Issue 17, May 3, 2024.The metabolomes of six Massilia strains were analyzed using a molecular‐networking guided approach, revealing interconnections among metabolites. A closer inspection of the most promising strains led to the discovery of novel N‐acylated amino acids, termed kyonggic acids.
Till Steinmetz +3 more
wiley +1 more source
Screening for Bioactive Compounds from Algae [PDF]
, 2012 At present, functional foods are seen as a good alternative to maintain or even improve human health, mainly for the well-known correlation between diet and health.
Herrero, Miguel +3 more
core +2 more sources
The Raputindoles: Novel Cyclopentyl Bisindole Alkaloids from Raputia simulans
Organic Letters, 2010 A novel class of bisindole alkaloids is established by the isolation and structural determination of raputindoles A-D (1-4) from the Amazonian plant Raputia simulans Kallunki (Rutaceae). Complete spectroscopic characterization was accomplished by means of NMR spectroscopy and APCI (+) HRMS.
Vougogiannopoulou, K. +4 more
openaire +3 more sources
Bis-indole chiral architectures for asymmetric catalysis
Nature CommunicationsChiral scaffolds are essential to the advancement of asymmetric synthesis, yet the development of privileged motifs that more effectively communicate asymmetry constitutes a grand challenge for chemists.
Junshan Lai +2 more
doaj +1 more source
A Simple Strategy for Obtaining Bis-Indole Derivatives under Solvent Free Conditions [PDF]
Journal of Chemistry LettersBis-indole, a biomolecule which has acquired its own place in heterocyclic chemistry because of remarkable biological properties.These derivatives can be synthesized by the reaction of indole having carbonyl compound like aldehydes and ketones in the ...
Praveen Mugali +4 more
doaj +1 more source
Plant-derived antimalarial agents: from crude extracts to isolated bioactive compounds [PDF]
, 2011 Despite decades of intense research, malaria remains a deadly disease of the developing worlds. Drugresistance to limited available antimalarials, in part, has contributed to the persistence of this infectious disease.
Abdullah, Wan Omar, Ismail, Patimah
core
Structure Elucidation and the Antimalarial Activity of Indole Alkaloids from Tabernaemontana macrocarpa Jack [PDF]
, 2021 星薬科大学博士（薬科学）doctoral ...
AMELIA, Puteri
core
Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings
Molecules, 2018 Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid ...
András Keglevich +8 more
doaj +1 more source