Results 21 to 30 of about 1,055 (166)

Crystal structure of diethyl 3,3′-[(4-nitrophenyl)methylene]bis(1H-indole-2-carboxylate)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, C29H25N3O6, the mean planes of the two indole ring systems (r.m.s. deviations = 0.0115 and 0.0082 Å) are approximately perpendicular to one another, making a dihedral angle of 89.7 (5)°; the benzene ring is twisted with respect to ...
Hong-Shun Sun   +4 more
doaj   +1 more source

Diethyl 3,3′-[(4-fluorophenyl)methylidene]bis(1H-indole-2-carboxylate)

open access: yesIUCrData, 2019
In the title compound, C29H25FN2O4, the mean planes of the indole ring systems (r.m.s. deviations = 0.0107 and 0.0158 Å) are approximately perpendicular to each other, subtending a dihedral angle of 87.43 (16)°. The 4-fluorophenyl ring is twisted by 77.6 
Yu-Long Li   +6 more
doaj   +1 more source

Crystal structure of diethyl 3,3′-[(2-fluorophenyl)methylidene]bis(1H-indole-2-carboxylate)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, C29H25FN2O4, the mean planes of the two indole ring systems (r.m.s. deviations = 0.1392 and 0.0115 Å) are approximately perpendicular to one another, subtending a dihedral angle of 86.0 (5)°; the benzene ring is twisted with ...
Xin-Hua Lu   +4 more
doaj   +1 more source

Antemitotic activity of strychnopentamine, a bisindolic alkaloid

open access: yesJournal of Ethnopharmacology, 1984
Strychnopentamine has been tested for its cytotoxic and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine group increases the antimitotic activity of this type of alkaloids.
Tits, Monique   +4 more
openaire   +3 more sources

Crystal structure of diethyl 3,3′-[(2,4-dichlorophenyl)methylidene]bis(1H-indole-2-carboxylate)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, C29H24Cl2N2O4, the mean planes of the two indole ring systems (r.m.s. deviations = 0.1249 and 0.0075 Å) are approximately perpendicular to one another, with a dihedral angle of 80.9 (5)° between them.
Yu-Long Li   +4 more
doaj   +1 more source

A Fluorinated Analogue of Marine Bisindole Alkaloid 2,2-Bis(6-bromo-1H-indol-3-yl)ethanamine as Potential Anti-Biofilm Agent and Antibiotic Adjuvant Against Staphylococcus aureus

open access: yesPharmaceuticals, 2020
Methicillin resistant Staphylococcus aureus (MRSA) infections represent a major global healthcare problem. Therapeutic options are often limited by the ability of MRSA strains to grow as biofilms on medical devices, where antibiotic persistence and ...
Raffaella Campana   +6 more
doaj   +1 more source

Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity

open access: yesMolecules, 2022
Isatin and its derivatives are important heterocycles found in nature and present in numerous bioactive compounds which possess various biological activities. Moreover, it is an essential building block in organic synthesis.
Francesca Bonvicini   +4 more
doaj   +1 more source

An Alkaloid from a Highly Invasive Seaweed Increases the Voracity and Reproductive Output of a Model Fish Species

open access: yesMarine Drugs, 2022
The invasive macroalga Caulerpa cylindracea has spread widely in the Mediterranean Sea, becoming a favorite food item for native fish for reasons yet unknown.
Valentina Schiano   +15 more
doaj   +1 more source

A new approach for the synthesis of bisindoles through AgOTf as catalyst

open access: yesBeilstein Journal of Organic Chemistry, 2014
A novel approach for the catalyzed formation of bisindolylmethane derivatives (BIMs) is described. This methodology is the unique example where AgOTf has been successfully used for the activation of aldehydes, giving easy access to a broad range of ...
Jorge Beltrá   +2 more
doaj   +1 more source

Synthesis of Bisindole Alkaloids from the Apocynaceae Which Contain a Macroline or Sarpagine Unit: A Review

open access: yesMolecules, 2016
Bisindole natural products consist of two monomeric indole alkaloid units as their obligate constituents. Bisindoles are more potent with respect to their biological activity than their corresponding monomeric units.
Md Toufiqur Rahman   +2 more
doaj   +1 more source

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