Results 31 to 40 of about 1,592 (193)
Diethyl 3,3′-[(3-fluorophenyl)methylene]bis(1H-indole-2-carboxylate)
In the title compound, C29H25FN2O4, the mean planes of the indole ring systems are approximately perpendicular to one another [dihedral angle = 88.3 (4)°]. The benzene ring is twisted with respect to the indole ring systems by 49.8 (5) and 77.6 (3)°.
Hong Jiang +7 more
doaj +1 more source
Novel Small-Molecule Hybrid-Antibacterial Agents against S. aureus and MRSA Strains
Ongoing resistance developments against antibiotics that also affect last-resort antibiotics require novel antibacterial compounds. Strategies to discover such novel structures have been dimerization or hybridization of known antibacterial agents.
Robin Gehrmann +5 more
doaj +1 more source
Octacycles and Nonacycles from 3Hydroxy-2,2-bisindole
3-Hydroxy-2,2′-bisindole undergoes acid- and base-mediated dimerization–skeletal rearrangement processes, generating polyheterocyclic ring systems containing up to nine rings.
Jonathan Sperry (619935) +5 more
core +1 more source
Discovery of Barakacin and Its Derivatives as Novel Antiviral and Fungicidal Agents
Pesticides are essential for the development of agriculture. It is urgent to develop green, safe and efficient pesticides. Bisindole alkaloids have unique and concise structures and broad biological activities, which make them an important leading ...
Yongyue Gao +11 more
doaj +1 more source
Two or more indole molecules tailored to a single non-metal central atom, through any of their C2–7 positions are not only structurally engaging but also constitute a class of important pharmacophores.
Ranadeep Talukdar
doaj +1 more source
N-Protected 3-iodoindoles were reacted with (di)azine halides in a sequentially Pd-catalyzed one-pot fashion, i.e., by Masuda borylation–Suzuki coupling (MBSC) sequence.
Marco Kruppa +2 more
doaj +1 more source
Crystal structure of diethyl 3,3′-[(2-fluorophenyl)methylidene]bis(1H-indole-2-carboxylate)
In the title compound, C29H25FN2O4, the mean planes of the two indole ring systems (r.m.s. deviations = 0.1392 and 0.0115 Å) are approximately perpendicular to one another, subtending a dihedral angle of 86.0 (5)°; the benzene ring is twisted with ...
Xin-Hua Lu +4 more
doaj +1 more source
Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury. [PDF]
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Zhu S, Zhong S, Lin X, Zhao C, Li Y.
europepmc +2 more sources
Crystal structure of diethyl 3,3′-[(4-nitrophenyl)methylene]bis(1H-indole-2-carboxylate)
In the title compound, C29H25N3O6, the mean planes of the two indole ring systems (r.m.s. deviations = 0.0115 and 0.0082 Å) are approximately perpendicular to one another, making a dihedral angle of 89.7 (5)°; the benzene ring is twisted with respect to ...
Hong-Shun Sun +4 more
doaj +1 more source
Diethyl 3,3′-[(4-fluorophenyl)methylidene]bis(1H-indole-2-carboxylate)
In the title compound, C29H25FN2O4, the mean planes of the indole ring systems (r.m.s. deviations = 0.0107 and 0.0158 Å) are approximately perpendicular to each other, subtending a dihedral angle of 87.43 (16)°. The 4-fluorophenyl ring is twisted by 77.6
Yu-Long Li +6 more
doaj +1 more source

