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Turkish Journal of Orthodontics, 2009 Bisphosphonates are used with the purpose of preventing bone resorption in some metabolic bone diseases. These drugs have been introduced into clinical use about 30 years ago and widely used in nowadays. As Orthodontic some different researches have been
Fırat Öztürk
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Carpal Tunnel Syndrome Associated with Oral Bisphosphonates. A Population-Based Cohort Study. [PDF]
PLoS ONE, 2016 BackgroundBisphosphonates are widely used to prevent osteoporotic fractures. Some severe musculoskeletal reactions have been described with this medication; among them, some cases of carpal tunnel syndrome.
Alfonso Carvajal +7 more
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Endocrinology and Metabolism Clinics of North America, 2003 Osteoporosis is the result of bone loss due to an imbalance in bone turnover such that bone resorption exceeds bone formation. Bisphosphonates are potent inhibitors of osteoclast activity that reduce bone turnover and re-establish the balance between bone resorption and formation. In clinical studies, several bisphosphonates prevent bone loss, preserve
Julie T, Lin, Joseph M, Lane
openaire +7 more sources
Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review. [PDF]
, 2013 Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint ...
AD Beswick +37 more
core +13 more sources
Annals of the New York Academy of Sciences, 2006 Abstract: Bisphosphonates belong to a class of compounds similar to pyrophosphate. In these compounds the oxygen atom of the pyrophosphate is replaced by a carbon atom resulting in a P‐C‐P bond. They exert a potent inhibitory effect on osteoclasts and are therefore potent antiresorptive agents. They reduce bone turnover, increase bone mineral density,
Lambrinoudaki, I. +2 more
+7 more sources
Frontiers in Chemistry, 2022 Phosphonates and bisphosphonates are stable analogs of phosphates and pyrophosphates that are characterized by one and two carbon–phosphorus bonds, respectively.
Babak Kaboudin +3 more
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Journal of Orthopaedic Translation, 2020 Objective: The objective of this study was to assess the efficacy and safety of denosumab therapy in osteoporotic postmenopausal women who were previously treated with bisphosphonates. Methods: Meta-analyses of four available randomised controlled trials
Yilin Zhu +9 more
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Therapeutic Advances in Chronic Disease, 2022 Background: Bisphosphonates are a type of medication that prevents the loss of bone density. Secondary childhood osteoporosis reduces bone strength and results in an increased risk of fragility fracture.
Huawei Zhao +5 more
doaj +1 more source
Atypical femur fractures associated with chronic bisphosphonates use: A case series with 66 patients [PDF]
Revista Brasileira de Ortopedia, 2022 Objective The present study aims to describe outcomes from a series of surgically treated patients with atypical femoral fracture due to bisphosphonates use, in addition to correlate the time of previous medication use with fracture consolidation time ...
Guilherme Guadagnini Falotico +5 more
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Enhanced osteogenic differentiation in zoledronate-treated osteoporotic patients [PDF]
, 2017 Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic ...
Carbonare, Luca Dalle +7 more
core +6 more sources