Results 51 to 60 of about 82,508 (316)

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

American Society of Clinical Oncology recommendations of Bisphosphonates administration and bone health issues in women with breast cancer. Part 1. Recommendations on Bisphosphonates use in the treatment of patients with breast cancer.

Опухоли женской репродуктивной системы, 2014
American Society of Clinical Oncology recommendations of Bisphosphonates administration and bone health issues in women with breast cancer.Part 1. Recommendations on Bisphosphonates use in the treatment of patients with breast cancer.
I. V. Vysotskaya
doaj   +1 more source

Patient level pooled analysis of 68,500 patients from seven major vitamin D fracture trials in the US and Europe [PDF]

, 2010
Objectives To identify participants’ characteristics that influence the anti-fracture efficacy of vitamin D or vitamin D plus calcium with respect to any fracture, hip fracture, and clinical vertebral fracture and to assess the influence of dosing ...
Abrahamsen, B, Anderson, F, Avenell, A, Brixen, K, Cooper, C, F, Hutchison, Francis, R M, Jackson, R, Johansen, A, LaCroix, A Z, Masud, T, Meyer, H E, Mosekilde, L, Rejnmark, L, Robbins, J A, Smith, H, The DIPART (vitamin D Individual Patient Analysis of Randomized Trials) Group, Torgerson, D, Wactawski-Wende, J   +18 more
core   +2 more sources

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Bisphosphonates in Total Joint Arthroplasty: A Review of Their Use and Complications

Arthroplasty Today, 2022
Background: Considerable interest has been expressed in the use of bisphosphonates to treat periprosthetic osteoporosis with the clinical goals of reducing periprosthetic fractures and prolonging implant survival.
Christopher L. McDonald, MD, Nicholas J. Lemme, MD, Edward J. Testa, MD, Roy Aaron, MD, Davis A. Hartnett, BS, Eric M. Cohen, MD   +5 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes. [PDF]

, 2017
Nitrogen-containing bisphosphonates (N-BPs) are the most widely used anti-resorptive agents in the treatment of bone-related diseases. N-BPs inhibit bone resorption by specifically targeting osteoclasts, bone-resorbing cells.
Kang, Mo K, Kim, Reuben H, Lee, Rachel S, Park, No-Hee, Shin, Ki-Hyuk, Sohn, Suhjin   +5 more
core   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Biological evaluations of novel 2,3,3-Trisphosphonate in osteoclastic and osteoblastic activities [PDF]

, 2017
Bisphosphonates (BPs) are the first line treatment for many bone diseases including hypercalcimia associated with bone malignancies. In this paper, we introduce a new analogue of bisphosphonate called the 2,3,3-Trisphosphonate (2,3,3-TriPP) that was ...
Boccaccini, Aldo R., Cheong, Yuen Ki, Detsch, Rainer, Huang, Mei, Ren, Guogang   +4 more
core   +3 more sources