Results 91 to 100 of about 2,300 (167)

High Frequency of Detection of NDM‐Producing Enterobacterales Among Companion Animals Hospitalized in an Italian Veterinary Teaching Hospital

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Carbapenems are considered one of the most important last‐resort classes of antibiotics, and the spread of carbapenem‐resistant Enterobacterales (CRE) is a serious concern worldwide. From a One Health point of view, reports on CRE in companion animals are increasing, requiring attention regarding their role in maintenance and direct transmission to ...
R. Scarpellini   +8 more
wiley   +1 more source

Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]

open access: yes, 2015
Objectives: Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum ...
Nordmann, Patrice   +2 more
core  

First Indian report on genome-wide comparison of multidrug-resistant Escherichia coli from blood stream infections. [PDF]

open access: yes, 2020
BACKGROUND: Multidrug-resistant (MDR) E. coli with extended-spectrum β-lactamases (ESBLs) is becoming endemic in health care settings around the world. Baseline data on virulence and antimicrobial resistance (AMR) of specific lineages of E.
Anandan, Shalini   +9 more
core   +4 more sources

The difficult-to-control spread of carbapenemase producers in Enterobacteriaceae worldwide [PDF]

open access: yes, 2014
Spread of carbapenemase producers in Enterobacteriaceae is now identified worldwide. Three main carbapenemases are reported which belong to three classes of ß-lactamases that are KPC, NDM and OXA-48.
Nordmann, Patrice, Poirel, Laurent
core  

Epidemiology and clinical significance of carbapenemases in Australia: a narrative review

open access: yesInternal Medicine Journal, Volume 54, Issue 4, Page 535-544, April 2024.
Abstract Carbapenemase‐producing gram‐negative bacteria (CP‐GNB) infections threaten public health with high mortality, morbidity and treatment costs. Although frequencies remain low in Australia (total number of CP‐GNB infections reported was 907 in 2022), blaIMP‐4 has established low levels of endemicity in many states.
Abdullah Tarik Aslan, David L. Paterson
wiley   +1 more source

Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying blaNDM-5 on an IncF Multidrug Resistance Plasmid and blaOXA-181 on an IncX3 Plasmid. [PDF]

open access: yesGenome announcements, 2018
Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored blaNDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and blaOXA-181E.
Overballe-petersen, Søren   +8 more
openaire   +3 more sources

Genetically Engineered Microorganisms and Their Impact on Human Health

open access: yesInternational Journal of Clinical Practice, Volume 2024, Issue 1, 2024.
The emergence of antibiotic‐resistant strains, the decreased effectiveness of conventional therapies, and the side effects have led researchers to seek a safer, more cost‐effective, patient‐friendly, and effective method that does not develop antibiotic resistance.
Marzie Mahdizade Ari   +5 more
wiley   +1 more source

Multidrug-resistant Klebsiella pneumoniae clinical isolates producing NDM- and OXA-type carbapenemase in Nepal

open access: yesJournal of Global Antimicrobial Resistance
Objectives: The emergence of multidrug-resistant Klebsiella pneumoniae has become a serious problem in medical settings worldwide. Methods: A total of 46 isolates of multidrug-resistant K.
Satomi Takei   +7 more
doaj   +1 more source

Phenotypic and genotypic characterization of clinical carbapenem-resistant Enterobacteriaceae isolates from Sokoto, northwest Nigeria

open access: yesNew Microbes and New Infections, 2020
Emergence and spread of carbapenemase-producing Enterobacteriaceae (CPE) are two of the major problems currently threatening global public health. In Nigeria, interest in CPE is recent.
A. Olowo-okere   +7 more
doaj   +1 more source

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