Results 91 to 100 of about 2,300 (167)
Carbapenems are considered one of the most important last‐resort classes of antibiotics, and the spread of carbapenem‐resistant Enterobacterales (CRE) is a serious concern worldwide. From a One Health point of view, reports on CRE in companion animals are increasing, requiring attention regarding their role in maintenance and direct transmission to ...
R. Scarpellini +8 more
wiley +1 more source
Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]
Objectives: Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum ...
Nordmann, Patrice +2 more
core
First Indian report on genome-wide comparison of multidrug-resistant Escherichia coli from blood stream infections. [PDF]
BACKGROUND: Multidrug-resistant (MDR) E. coli with extended-spectrum β-lactamases (ESBLs) is becoming endemic in health care settings around the world. Baseline data on virulence and antimicrobial resistance (AMR) of specific lineages of E.
Anandan, Shalini +9 more
core +4 more sources
The difficult-to-control spread of carbapenemase producers in Enterobacteriaceae worldwide [PDF]
Spread of carbapenemase producers in Enterobacteriaceae is now identified worldwide. Three main carbapenemases are reported which belong to three classes of ß-lactamases that are KPC, NDM and OXA-48.
Nordmann, Patrice, Poirel, Laurent
core
Epidemiology and clinical significance of carbapenemases in Australia: a narrative review
Abstract Carbapenemase‐producing gram‐negative bacteria (CP‐GNB) infections threaten public health with high mortality, morbidity and treatment costs. Although frequencies remain low in Australia (total number of CP‐GNB infections reported was 907 in 2022), blaIMP‐4 has established low levels of endemicity in many states.
Abdullah Tarik Aslan, David L. Paterson
wiley +1 more source
Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying blaNDM-5 on an IncF Multidrug Resistance Plasmid and blaOXA-181 on an IncX3 Plasmid. [PDF]
Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored blaNDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and blaOXA-181E.
Overballe-petersen, Søren +8 more
openaire +3 more sources
Genetically Engineered Microorganisms and Their Impact on Human Health
The emergence of antibiotic‐resistant strains, the decreased effectiveness of conventional therapies, and the side effects have led researchers to seek a safer, more cost‐effective, patient‐friendly, and effective method that does not develop antibiotic resistance.
Marzie Mahdizade Ari +5 more
wiley +1 more source
Objectives: The emergence of multidrug-resistant Klebsiella pneumoniae has become a serious problem in medical settings worldwide. Methods: A total of 46 isolates of multidrug-resistant K.
Satomi Takei +7 more
doaj +1 more source
Emergence and spread of carbapenemase-producing Enterobacteriaceae (CPE) are two of the major problems currently threatening global public health. In Nigeria, interest in CPE is recent.
A. Olowo-okere +7 more
doaj +1 more source

