Results 81 to 90 of about 2,300 (167)
We identified and characterised AMM‐1, a novel metallo‐β‐lactamase from Alteromonas mangrovi in the Yangtze River Estuary. AMM‐1 clusters with clinically relevant MBLs. Structural modelling reveals a conserved di‐zinc active site essential for β‐lactam hydrolysis; AMM‐1 shows distinct active‐site flexibility compared with representative MBLs ...
Xuan Wu +5 more
wiley +1 more source
Detection of OXA-181/OXA-48 carbapenemase producing Enterobacteriaceae in Bangladesh
Carbapenem resistant Enterobacteriaceae (CRE) is becoming a major public health concern globally. Detection of carbapenem hydrolyzing enzyme carbapenemase in Enterobacteriaceae is important to institute appropriate therapy and to initiate preventive ...
Rehana Khatun, S.M. Shamsuzzaman
doaj
Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]
Objectives Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum cephalosporins.
Nordmann, Patrice +2 more
core
NDM-5 and OXA-181 Beta-Lactamases, a Significant Threat Continues To Spread in the Americas [PDF]
Among Gram-negative bacteria, carbapenem-resistant infections pose a serious and life-threatening challenge. Here, the CRACKLE network reports a sentinel detection and characterization of a carbapenem-resistant Klebsiella pneumoniae ST147 isolate ...
Adams, Mark D. +12 more
core +2 more sources
Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022 [PDF]
Whole genome sequencing data of 874 Escherichia coli isolates carrying blaNDM-5 from 13 European Union/ European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and ...
Alm, Erik +29 more
core +3 more sources
The rapid emergence of carbapenemase-producing gram-negative bacteria (CPGNB) is a global threat due to the high mortality of infection and limited treatment options. Although there have been many reports of CPGNB isolated from Southeast Asian countries,
Aki Hirabayashi +12 more
doaj +1 more source
The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Brink AJ +5 more
core +2 more sources
A Whole-Genome Sequencing-Based Approach for the Characterization of Klebsiella pneumoniae Co-Producing KPC and OXA-48-like Carbapenemases Circulating in Sardinia, Italy [PDF]
Background: Whole-genome sequencing (WGS) provides important information for the characterization, surveillance, and monitoring of antimicrobial resistance (AMR) determinants, particularly in cases of multi- and extensively drug-resistant microorganisms.
Alteri C. +10 more
core +1 more source
Abstract This report presents the main findings of the 2022–2023 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans and food‐producing animals (broilers, laying hens and fattening turkeys, fattening pigs and cattle under 1 year of age) and derived meat.
European Food Safety Authority +1 more
wiley +1 more source
Nosocomial Outbreak Caused by NDM-5 and OXA-181 Carbapenemase Co-producing Escherichia coli [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant ...
홍준성
core +1 more source

