Results 141 to 150 of about 19,187 (211)

Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1α-deficient mouse embryonic fibroblasts [PDF]

, 2017
A mismatch between metabolic demand and oxygen delivery leads to microenvironmental changes in solid tumors. The resulting tumor hypoxia is associated with malignant progression, therapy resistance and poor prognosis.
Balamurugan, Kuppusamy, Stiehl, Daniel P., Wenger, Roland H., Wirthner, Renato, Wrann, Simon   +4 more
core  

Pajanan Hipoksia Hipobarik Intermiten Menurunkan Metabolisme Anaerobik Pada Tikus Jantan Spraque Dawley [PDF]

, 2010
Hipoksia hipobarik intermiten (HHI) sering dialami oleh para penerbang maupun awak pesawat. Jika hipoksia berlanjut, maka terjadi metabolisme anaerobik yang berlebihan dan gangguan pada mitokondria yang menyebabkan apoptosis.
Achmad, T. H. (Tri), Hernowo, B. S. (Bethy), Hidayat, A. (Achmad), Wiradisastra, K. (Kahdar)   +3 more
core  

BNIP3 wt Allele [PDF]

, 2020
openaire   +1 more source

Alternative BNIP3 splicing in alveolar rhabdomyosarcomal cells

, 2023
Several cellular phenotypes drive tumorigenesis in alveolar rhabdomyosarcoma. These phenotypes may be attenuated via treatment with non-steroidal antiinflammatory drugs, like aspirin, tolfenamic acid, and indomethacin, which interfere with intracellular prostaglandin synthesis and induce cell death.
openaire   +1 more source

Association of HIF1α, BNIP3, and BNIP3L with Hypoxia-Related Metabolic Stress in Metabolic Syndrome. [PDF]

Medicina (Kaunas)
Kıran TR, Keskin L, Erdem M, Güçtekin Z, İnceoğlu F.   +4 more
europepmc   +1 more source

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source

Mitochondria-specific targeting of noncanonical <i>EGR1</i> ntmRNA-coordinated mitophagy receptor BNIP3 homodimerization disrupts mitochondrial metabolism and suppresses hepatocellular carcinoma growth <i>in vitro</i> and <i>in vivo</i>. [PDF]

Theranostics
Li Y, Zhou L, Liu M, Li H, Meng Y, Wen X, Zhao Y, Liu S, Yan Z, Fu C, Zong S, Li W, Hoffman AR, Cui J, Hu JF.   +14 more
europepmc   +1 more source

Astragalus polysaccharide alleviates diabetic nephropathy via SIRT1-dependent activation of FOXO3a/BNIP3 pathway to enhance podocyte autophagy. [PDF]

Sci Rep
Guo M, Dai Y, Zhuang X.
europepmc   +1 more source

Enhancement of Hypoxia-Induced Autophagy via the HIF-1apha/BNIP3 Pathway Promotes Proliferation and Myogenic Differentiation of Aged Skeletal Muscle Satellite Cells. [PDF]

Life (Basel)
Zhou L, Feng C, Lin J, Geng M, Qu D, Xing J, Lin H, Ma X, Nakanishi R, Maeshige N, Kondo H, Fujino H.   +11 more
europepmc   +1 more source

Methylmalonate accumulation contributes to myocardial vulnerability post-reperfusion: a novel therapeutic target and prognostic biomarker. [PDF]

BMC Med
Wang S, Guo J, Wang Z, Chen K, Liu X, Cui Y, Wang Y, Li Z, Cai H, Ma G, Zhang Z, Wang G, Xiu L, Li S, Li H, Jia H, Yu B, Fang S.   +17 more
europepmc   +1 more source