Results 171 to 180 of about 21,955 (252)

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source

Mitochondria-specific targeting of noncanonical <i>EGR1</i> ntmRNA-coordinated mitophagy receptor BNIP3 homodimerization disrupts mitochondrial metabolism and suppresses hepatocellular carcinoma growth <i>in vitro</i> and <i>in vivo</i>. [PDF]

Theranostics
Li Y, Zhou L, Liu M, Li H, Meng Y, Wen X, Zhao Y, Liu S, Yan Z, Fu C, Zong S, Li W, Hoffman AR, Cui J, Hu JF.   +14 more
europepmc   +1 more source

Astragalus polysaccharide alleviates diabetic nephropathy via SIRT1-dependent activation of FOXO3a/BNIP3 pathway to enhance podocyte autophagy. [PDF]

Sci Rep
Guo M, Dai Y, Zhuang X.
europepmc   +1 more source

Mastering cardiomyocyte mitophagy: molecular governance, pathological derailment and therapeutics. [PDF]

PeerJ
Liu P, Wu H, Ren H, Wang J, Yang F.
europepmc   +1 more source

Functional Dissection of BH3 Only Protein BNIP3

Functional Dissection of BH3 Only Protein BNIP3
BNIP3 is a pro-apoptotic protein, which contains BH3 and trans-membrane domains. Previous studies demonstrated an association between ceBNIP3, C. elegans homologue of BNIP3, and ced-3. It seemed likely that the interaction between ceBNIP3 and ced-3 was an alternative cascade of caspase activation in C.
openaire  

Enhancement of Hypoxia-Induced Autophagy via the HIF-1apha/BNIP3 Pathway Promotes Proliferation and Myogenic Differentiation of Aged Skeletal Muscle Satellite Cells. [PDF]

Life (Basel)
Zhou L, Feng C, Lin J, Geng M, Qu D, Xing J, Lin H, Ma X, Nakanishi R, Maeshige N, Kondo H, Fujino H.   +11 more
europepmc   +1 more source

Hsa_circ_0101645 contributes to excessive autophagy and apoptosis in intervertebral disc degeneration by acting as a miR-1304-5p sponge modulating BNIP3 expression. [PDF]

Noncoding RNA Res
Luo J, Yu T, Hu P, Liu J.
europepmc   +1 more source

Methylmalonate accumulation contributes to myocardial vulnerability post-reperfusion: a novel therapeutic target and prognostic biomarker. [PDF]

BMC Med
Wang S, Guo J, Wang Z, Chen K, Liu X, Cui Y, Wang Y, Li Z, Cai H, Ma G, Zhang Z, Wang G, Xiu L, Li S, Li H, Jia H, Yu B, Fang S.   +17 more
europepmc   +1 more source

The Role of HIF-1α/BNIP3 Pathway in Hippocampal Neuronal Autophagy in Epilepsy. [PDF]

Mol Neurobiol
Kuang H, Meng Y, Qin X, Qian K, Gong C, Li S, Zhang L, Gan X, Lu Y, Wu Y.   +9 more
europepmc   +1 more source

Methylated BNIP3 gene in colorectal cancer prognosis

Methylated BNIP3 gene in colorectal cancer prognosis
The DNA methylation of apoptosis-related genes in various cancers contributes to the disruption of the apoptotic pathway and results in resistance to chemotherapeutic agents. Irinotecan (CPT-11) is one of the key chemotherapy drugs used to treat metastatic colorectal cancer (CRC).
openaire