Results 31 to 40 of about 13,811 (214)
Post-Translational Control of BNIP3 and Mitophagy by ULK1 Kinase [PDF]
, 2021 BNIP3 is a mitochondrial cargo receptor that specifically targets mitochondria for degradation at the autolysosome through a specialized form of autophagy called mitophagy.
Poole, Logan Patrick
core +1 more source
Cells, 2019 : Stem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and neurogenic lineages.
Murielle Rémy +8 more
doaj +1 more source
Cell Death and Disease, 2022 Embryonic stem cells (ESCs) have a significantly lower mutation load compared to somatic cells, but the mechanisms that guard genomic integrity in ESCs remain largely unknown.
Qian Zhao +9 more
doaj +1 more source
Deficit of female sex hormones desensitizes rat cardiac mitophagy
Chinese Journal of Physiology, 2021 Long-term deprivation of female sex hormones has been shown to mediate accumulation of damaged mitochondria in ventricular muscle leading to cardiovascular dysfunction.
Theerachat Kampaengsri +3 more
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Autophagy and BNIP3 protein in tumorogenesis
Postępy Higieny i Medycyny Doświadczalnej, 2013 Autophagy is a process necessary for maintaining cell homeostasis in physiological conditions, as well as during certain stresses like nutrients or oxygen deprivation. Autophagy also plays an essential role in tumorigenesis. It prevents cell transformation, but on the other hand, autophagy enables existing cancer cells to adapt to harmful conditions ...
Ewelina, Swiderek, Leon, Strządała
openaire +2 more sources
Regulation of BNIP3 in Normal and Cancer Cells
Molecules and Cells, 2006 Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) is a mitochondrial pro-apoptotic protein that has a single Bcl-2 homology 3 (BH3) domain and a COOH-terminal transmembrane (TM) domain. Al-though it belongs to the Bcl-2 family and can hetero-dimerize with Bcl-2, its pro-apoptotic activity is distinct from those of other members of the Bcl-2 ...
Hayyoung, Lee, Sang-Gi, Paik
openaire +2 more sources
The effect of 4 weeks of continuous aerobic training with different volumes and starvation on the expression of some genes involved in liver mitophagy in healthy male Wistar rats [PDF]
ورزش و علوم زیست حرکتیIntroduction and Purpose: An increase in the number of defective mitochondria and their persistence can lead to apoptosis and necrosis of cells. Regular physical exercise along with time-restricted eating (TRE) can play an important role in improving ...
Hamzeh Bayani +3 more
doaj +1 more source
BNIP3 contributes to cisplatin‐induced apoptosis in ovarian cancer cells
FEBS Open Bio, 2020 BNIP3 is a proapoptotic protein that mediates apoptosis, necrosis and autophagy. However, the involvement of BNIP3 in cisplatin‐induced apoptosis in ovarian cancer is not clear.
Jinghui Jia +6 more
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A crosstalk between phosphorylation and ubiquitination of BNIP3 regulates mitophagy under hypoxia
Autophagy Reports, 2023 BNIP3 (BCL2/adenovirus e1B 19 kDa protein interacting protein 3) is a mitochondrial outer membrane protein that is sensitive to hypoxia and mediates mitophagy, a process important for mitochondrial quality control and to maintain energetic and redox ...
Yun-Ling He +4 more
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Expression and Functional Characterization of the BNIP3 Protein in Renal Cell Carcinomas
Translational Oncology, 2017 BNIP3 (Bcl-2/adenovirus E1B 19-kDa interacting protein 3) is a BH3-only protein that regulates apoptosis and autophagy. BNIP3 plays also an important role in hypoxia-induced cell response and is regulated by HIF1.
Stephan Macher-Goeppinger +6 more
doaj +1 more source