Results 151 to 160 of about 76,436 (252)

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

3D-printed ion-engineered TaTiCu porous scaffolds for promoting bone defect repair

Jie Jiang, Mingxia Wang, Chaoqun You, Fanwei Zeng, Ling Ren, Xiaodong Tang, Yu Guo   +6 more
openalex   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Multifunctional Bioactive Scaffold Facilitating BMSCs-Driven Osteogenesis and Vascularization in Critical-Sized Bone Defect Repair. [PDF]

Adv Sci (Weinh)
Feng Y, Chen B, Xu Y, Xu X, Hu B, Li T, Zhang D, Bai B, Liu C, Xu W, Li L, Zhang W, Si H.   +12 more
europepmc   +1 more source

A piezoelectrically driven hierarchical biomimetic architecture promotes diabetic bone defect repair by bidirectionally regulating HIF-1α to restore immunometabolic-vascular homeostasis

Nanning Lv, He Dong, Haifu Sun, Jing Shi, Xinhui Wu, Xiaofan Chen, Hongye Li, Xiaoxiao Feng, Xuran Guo, Xieping Dong, Ying Hu, 郑龙坡, Mingming Liu   +12 more
openalex   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Biomimetic Chitosan/Polyvinyl Alcohol-Glycerol Scaffolds Inspired by Porcupine Quills for Segmental Bone Defect Repair. [PDF]

J Funct Biomater
Yang J, Zhao Z, Song Z, Cao L, Mei X, Zhang X.   +5 more
europepmc   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

Biodegradable Mg²⁺-releasing piezoelectric scaffold for segmental bone defect repair. [PDF]

Bioact Mater
Wang C, Zhang T, Liu J, Wang X, Gao C, Chen J, Feng J, Dong Z, Wang X, Li Y, Zhao M, Li F, Yu Y, Cai Q, Tian H.   +14 more
europepmc   +1 more source

A hybrid tissue engineering construct enabling sustained BMP2 delivery outperforms a clinically used collagen sponge in large bone defect repair: A preclinical study

Hirotsugu Maekawa, Seyedsina Moeinzadeh, Elaine Lui, Tomohiro Uno, Hossein Vahid Alizadeh, Jiannan Li, Á. Perez, Richard Sammy Muniz, Sungwoo Kim, Ashley M. Potter, Chloe Brekhus, Dan Regan, Drew W. Koch, Masanori Kobayashi, Toshiyuki Kawai, Shuichi Matsuda, Benjamin C. Gadomski, Jeremiah T. Easley, Jeffrey L. Young, Michael J. Gardner, David Glenn Mohler, William J. Maloney, Yunzhi Yang   +22 more
openalex   +1 more source