Results 181 to 190 of about 76,436 (252)

From damage control to definitive reconstruction: biomaterials in traumatic bone defect repair [PDF]

Hao Fang, Pengfei Cai, Biqian Ye, Jinhua Wang, Wenlin Xie, Endong Tao, Minli Hu   +6 more
openalex   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Preparation of TiO2 nanofillers-loaded Injectable Hydrogel functionalized with ADSCs-exosomes for bone defect repair by triggering the Wnt/β-catenin signaling pathway in vitro

Yi-wen Xu, Yi-wen Xu, Yiming Zhang, Haixia Liu, Hang Yuan, Nian Zhou, J. Zhang, Yuan-zhi Xu, Yuan-zhi Xu   +8 more
openalex   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Photothermal-driven multifunctional injectable hydrogel platform for promoting diabetic bone defect repair through synergistic immunomodulation and bone homeostasis. [PDF]

Theranostics
Zhu Y, Liu H, Yang Z, He Y, Wu P, Cai L, Yao L, Zhu X, Wu M.   +8 more
europepmc   +1 more source

Coordination chemistry-driven dynamic crosslinked hydrogel platform with ROS/pH responsiveness and photothermal activity for osteoporotic bone defect repair

Zhiqiang Yang, Yufan Zhu, Han Yu, Lin Cai, Ping Wu, Xiaozhen Lu, Minhao Wu   +6 more
openalex   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

SA/HA double-network hydrogel combined with PVDF electret membrane enhances osteogenic differentiation of DPSCs and promotes mandibular bone defect repair. [PDF]

Regen Ther
Zheng K, Xiao J, Qian J, Feng G, Zhang X, Huang D, Shi S, Xu K.   +7 more
europepmc   +1 more source

A New Ordered Transformation‐Induced Plasticity Enables Exceptional Strength and Ductility in a B2 Medium‐Entropy Alloy

Advanced Science, EarlyView.
A novel B2‐ordered Ti‐Zr‐V‐Al medium‐entropy intermetallic is developed through controlled metastability engineering, which activates an ordered TRIP effect via a new B2→D019‐α2 transformation with a distinctive {0001}α2//{110}B2, <11‐20>α2//<100>B2 orientation relationship. This alloy achieves an elongation of ∼7%, a strength of ∼1.1 GPa, and superior
Chaohua Li, Yidong Wu, Boyuan Zheng, Xu Zhang, Xiongjun Liu, Wenli Song, Ning An, Chengbo Xiao, Xidong Hui   +8 more
wiley   +1 more source

Ultrashort wave therapy promotes the repair of jaw defect by regulating the function of jaw bone marrow mesenchymal stromal cells

Liu Liu, Qian Zhao, Jin Liu, Huaqiang Ruan, Zhenshan Du, Xu Liu, Chuang Xu, Ruoyan Zhang, Li Haodi, Chunkai Ma, Feifei Tao, Xiaoxia Jiang, Lulu Xu   +12 more
openalex   +1 more source