Results 21 to 30 of about 27,645,133 (294)

Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells

Journal of Tissue Engineering, 2012
The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau, Mimmi Patrikoski, Miia Juntunen, Kasperi Kujala, Minna Kääriäinen, Hannu Kuokkanen, George K Sándor, Outi Vapaavuori, Riitta Suuronen, Bettina Mannerström, Brigitte von Rechenberg, Susanna Miettinen   +11 more
doaj   +1 more source

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Bone Morphogenetic Protein 1 Prodomain Specifically Binds and Regulates Signaling by Bone Morphogenetic Proteins 2 and 4 [PDF]

Journal of Biological Chemistry, 2007
Highly purified fractions of bone extracts capable of inducing ectopic bone formation have been reported to contain peptides corresponding to the mature active regions of the TGF-beta-like bone morphogenetic proteins (BMPs) 2-7, and to the prodomain region of the metalloproteinase BMP1.
Reema, Jasuja, Gaoxiang, Ge, Nikolas G, Voss, Jamie, Lyman-Gingerich, Amanda M, Branam, Francisco J, Pelegri, Daniel S, Greenspan   +6 more
openaire   +2 more sources

An osteoinductive and biodegradable intramedullary implant accelerates bone healing and mitigates complications of bone transport in male rats

Nature Communications, 2023
Bone transport is a surgery-driven procedure for the treatment of large bone defects. However, challenging complications include prolonged consolidation, docking site nonunion and pin tract infection.
Sien Lin, Hirotsugu Maekawa, Seyedsina Moeinzadeh, Elaine Lui, Hossein Vahid Alizadeh, Jiannan Li, Sungwoo Kim, Michael Poland, Benjamin C. Gadomski, Jeremiah T. Easley, Jeffrey Young, Michael Gardner, David Mohler, William J. Maloney, Yunzhi Peter Yang   +14 more
doaj   +1 more source

Bone Morphogenetic Protein as Bone Additive around Dental Implant and its Impact on Osseointegration: a Systematic Review [PDF]

Journal of Dentistry, 2022
Statement of the Problem: Bone morphogenetic protein (BMP), a potential osteoinductive agent, was systematically reviewed for merits and demerits when used as a bone additive that was intervened during the surgical phase of dental implant placement; and ...
Fathima Banu Raza , Sivakumar Vijayaragavalu , Anand Kumar Vaidyanathan   +2 more
doaj   +1 more source

Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]

, 2005
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core   +1 more source

The Use of Recombinant Bone Morphogenetic Protein-2 in the Treatment of Spondylodiscitis. [PDF]

Global Spine J
Study Design Retrospective observational cohort. Objective Although recombinant human bone morphogenetic protein-2 (rhBMP-2) has been shown to enhance fusion rates in spinal fusion surgery, its use in patients with spondylodiscitis ...
Nishizawa M, Djurasovic M, Glassman SD, Dimar JR, Crawford CH, Kostic B, Carreon LY.   +6 more
europepmc   +4 more sources

The Effect of NELL1 and Bone Morphogenetic Protein-2 on Calvarial Bone Regeneration [PDF]

Journal of Oral and Maxillofacial Surgery, 2010
Most craniofacial birth defects contain skeletal components that require bone grafting. Although many growth factors have shown potential for use in bone regeneration, bone morphogenetic proteins (BMPs) are the most osteoinductive. However, supraphysiologic doses, high cost, and potential adverse effects stimulate clinicians and researchers to identify
Tara, Aghaloo, Catherine M, Cowan, Xinli, Zhang, Earl, Freymiller, Chia, Soo, Benjamin, Wu, Kang, Ting, Zhiyuan, Zhang   +7 more
openaire   +2 more sources

EXPERIMENTAL ESTIMATION OF COMPOSITE MATERIAL CONTAINING THE PROTEIN-MINERAL COMPONENTS AND RECOMBINANT BONE MORPHOGENETIC PROTEIN-2 AS A COVERING OF TITANIUM IMPLANTS

Travmatologiâ i Ortopediâ Rossii, 2011
The influence of both, the composite material based on the protein-mineral components including the prolonged form of the recombinant human bone morphogenetic protein 2 (rhBMP-2) and the method of the titanium implant’s surface treatment, on the ...
M. Z. Fedorova, S. V. Nadezhdin, A. S. Semikhin, M. A. Lazebnaya, G. V. Khramov, Y. R. Kolobov, A. V. Gromov, M. S. Bartov, V. G. Lunin, A. S. Karyagina, D. V. Gunderov   +10 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]

, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk, Marzi, Ingo, Seebach, Caroline, Flinspach, Armin Niklas, Wenger, Florian, Warzecha, Jörg   +5 more
core   +1 more source