Results 11 to 20 of about 11,682,231 (209)
Synthetic and Systems Biotechnology, 2018 Although most in vitro (cell-free) synthetic biology projects are usually used for the purposes of fundamental research or the formation of high-value products, in vitro synthetic biology platform, which can implement complicated biochemical reactions by
Ting Shi +3 more
doaj +4 more sources
Amphiphilic DNA nanostructures for bottom-up synthetic biology. [PDF]
Chem Commun (Camb), 2021 DNA nanotechnology enables the construction of sophisticated biomimetic nanomachines that are increasingly central to the growing efforts of creating complex cell-like entities from the bottom-up.
Rubio-Sánchez R +3 more
europepmc +6 more sources
Bottom-up synthetic biology: modular design for making artificial platelets. [PDF]
Phys Biol, 2017 Engineering artificial cells to mimic one or multiple fundamental cell biological functions is an emerging area of synthetic biology. Reconstituting functional modules from biological components in vitro is a challenging yet an important essence of ...
Majumder S, Liu AP.
europepmc +5 more sources
Synthetic Biology: Bottom-Up Assembly of Molecular Systems. [PDF]
Chemical Reviews, 2022 The bottom-up assembly of biological and chemical components opens exciting opportunities to engineer artificial vesicular systems for applications with previously unmet requirements.
Ward, Thomas R +12 more
core +5 more sources
Physicochemical considerations for bottom-up synthetic biology. [PDF]
Emerg Top Life Sci, 2019 The bottom-up construction of synthetic cells from molecular components is arguably one of the most challenging areas of research in the life sciences. We review the impact of confining biological systems in synthetic vesicles.
Śmigiel WM, Lefrançois P, Poolman B.
europepmc +6 more sources
Special issue on bottom-up synthetic biology [PDF]
ChemBioChem, 2019 Bottom-up synthetic biology uses both biological and artificial chemical building blocks to create biomimetic systems, including artificial cells.
Tang, T. +7 more
core +5 more sources
Bottom-Up Construction of Complex Biomolecular Systems With Cell-Free Synthetic Biology [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Cell-free systems offer a promising approach to engineer biology since their open nature allows for well-controlled and characterized reaction conditions. In this review, we discuss the history and recent developments in engineering recombinant and crude
Nadanai Laohakunakorn +6 more
doaj +9 more sources
Can bottom-up synthetic biology generate advanced drug-delivery systems? [PDF]
Trends in Biotechnology, 2020 Nanomedicine has demonstrated the potential of nanotechnology in treating diseases by selectively targeting pathogenic cells and releasing their cargo on site, but the complexity of molecular engineering such drug-delivery vehicles impedes their broad ...
Lussier, F. +7 more
core +8 more sources
Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications [PDF]
Journal of Industrial Microbiology and Biotechnology, 2018 Synthetic biologists use engineering principles to design and construct genetic circuits for programming cells with novel functions. A bottom-up approach is commonly used to design and construct genetic circuits by piecing together functional modules ...
Tara L Deans, Mitchell S Weisenberger
core +3 more sources
Construction of membrane-bound artificial cells using microfluidics: a new frontier in bottom-up synthetic biology. [PDF]
Biochem Soc Trans, 2016 The quest to construct artificial cells from the bottom-up using simple building blocks has received much attention over recent decades and is one of the grand challenges in synthetic biology.
Elani Y.
europepmc +6 more sources