Results 21 to 30 of about 1,891 (175)

Antitoxins and botulinum toxin treatment. [PDF]

BMJ, 1992
Peter Hambleton, Hart Cohen, B. Palmer, J. Melling   +3 more
openalex   +4 more sources

Combined treatment with antitoxin and 3,4-diaminopyridine improves survival outcomes after lethal botulinum neurotoxin challenge. [PDF]

Mol Med
O'Brien SW, Gregg BM, Bollapragada A, McNutt PM.   +3 more
europepmc   +3 more sources

Chronic Botulism in Humans: A Case Series. [PDF]

Clin Case Rep
ABSTRACT This study presents novel clinical presentations of botulism, observed in both patients and goats from the same farm. Their symptoms appeared at the same time, suggesting a possible relation to animal visceral botulism. Interestingly, weight loss and weakness were the persistent signs, but not life‐threatening as expected in botulism.
Barzegar MS, Pourhemmati S, Mardani M.
europepmc   +2 more sources

Cauda equina nerve root enhancement in adult intestinal toxemia botulism [PDF]

BMC Neurology
Background Adult botulism is a rare, life-threatening condition typically caused by exposure to preformed botulinum neurotoxin (BoNT). Acute intestinal toxemia botulism (AITB) is an uncommon subtype resulting from colonization of Clostridium botulinum in
Ruiji Jiang, Benjamin Beland, Vinil Shah, Min Kang, Douglas B. Pet   +4 more
doaj   +2 more sources

Detection of a streptogramin A O-acetyltransferase gene (vatD) in the chromosome of Clostridium botulinum isolated from infants in the United States [PDF]

Applied and Environmental Microbiology
Infant botulism, the most common form of botulism in the United States, occurs when botulinum toxin-producing clostridia colonize the infant’s gut and produce botulinum neurotoxin (BoNT).
Ana Rafaela Kruemmel, Jessica L. Halpin, Victoria M. Foltz, Janet K. Dykes, Carolina Lúquez   +4 more
doaj   +2 more sources

Infant Botulism: A Case Study in Integrated Clinical and Public Health Response. [PDF]

Clin Case Rep
ABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
Gannon J, Fallon Verbruggen T, Burke S, Loughlin L, Brits C, Tedford K, McHugh JC, Mayberry H, O'Regan M, Freyne B, Conroy N.   +10 more
europepmc   +2 more sources

First case of infant botulism in Sicily—case report [PDF]

Italian Journal of Pediatrics
Background Botulism is a rare and life-threatening disease caused by the potent botulinum neurotoxin (BoNT), which can be produced by Clostridium botulinum (C. botulinum) and related bacteria.
Antonino Fazzino, Carmelinda Cavallaro, Francesca Cavataio, Giulia Linares, Antonina Lo Cascio, Carla Lo Porto, Giuseppe Santangelo, Laura Venuti, Giovanni Corsello, Claudia Colomba   +9 more
doaj   +2 more sources

Diagnosis and treatment of botulism after botulinum toxin type A injections: report of 9 cases

Di-san junyi daxue xuebao, 2021
Objective To explore the diagnostic criteria of botulism after botulinum toxin type A (BT/A) injection and observe the therapeutic effect of botulinum antitoxin.
HE Ping, ZHANG Jianghe, YAN Rongshuai, FAN Dongli, WANG Shaoliang, MAO Tongchun   +5 more
doaj   +1 more source

Clostridium botulinum – like organism bacteremia in a user of black tar heroin

IDCases, 2021
Wound botulism due to introduction of the anaerobic bacteria, Clostridium botulinum, into otherwise sterile, relatively anaerobic tissue is a known complication of black tar heroin use.
Therese Battiola, Kristen Saad, Taylor Nelson, Nick Tinker, Aaron Crosby   +4 more
doaj   +1 more source

A Rabbit Model for the Evaluation of Drugs for Treating the Chronic Phase of Botulism

Toxins, 2021
Antitoxin, the only licensed drug therapy for botulism, neutralizes circulating botulinum neurotoxin (BoNT). However, antitoxin is no longer effective when a critical amount of BoNT has already entered its target nerve cells.
Amram Torgeman, Eran Diamant, Eyal Dor, Arieh Schwartz, Tzadok Baruchi, Alon Ben David, Ran Zichel   +6 more
doaj   +1 more source