Results 31 to 40 of about 1,891 (175)

A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice

Toxins, 2023
Equine-derived antitoxin (BAT®) is the only treatment for botulism from botulinum neurotoxin serotype G (BoNT/G). BAT® is a foreign protein with potentially severe adverse effects and is not renewable.
Yongfeng Fan, Jianlong Lou, Christina C. Tam, Weihua Wen, Fraser Conrad, Priscila Leal da Silva Alves, Luisa W. Cheng, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, James D. Marks   +9 more
doaj   +1 more source

Iatrogenic Botulism After Cosmetic Use of Botulinum Toxin-A: A Case Series. [PDF]

Clin Case Rep
ABSTRACT Botulism symptoms after cosmetic botulinum toxin‐A (BTX‐A) injections happen very rarely, and it needs careful attention since it can be life‐threatening. Hence, it is advised to meticulously check the technique, dose, and authenticity of the BTX‐A before injections to reduce the adverse effects.
Asadi M, Shadnia S, Mostafazadeh B, Evini PET, Zandieh F, Rahimi M.   +5 more
europepmc   +2 more sources

Therapeutic efficacy of equine botulism antitoxin in Rhesus macaques. [PDF]

PLoS ONE, 2017
There are currently no licensed vaccines available for prevention of botulism in humans. The vaccination is not desirable due to expanding therapeutic indications of botulinum toxins.
Shantha Kodihalli, Andrew Emanuel, Teresa Takla, Yi Hua, Charles Hobbs, Ross LeClaire, Denise C O'Donnell   +6 more
doaj   +1 more source

Wound Botulism Caused by Botulinum Neurotoxin Type A in a Chronic Parenteral Drug Abuser

Case Reports in Neurology, 2020
Botulism is an acute paralytic disease caused by botulinum neurotoxin (BoNT)-mediated inhibition of neurosignaling at the neuromuscular junction. BoNTs are produced by gram positive, anaerobic, spore-forming bacteria from the genus Clostridium,most ...
Sohun Awsare, David Chirikian, Forshing Lui   +2 more
doaj   +1 more source

Botulism outbreak in a rural Ethiopia: a case series

BMC Infectious Diseases, 2021
Background Foodborne botulism, a toxin-mediated illness caused by Clostridium botulinum, is a public health emergency. Types A, B, and E C. botulinum toxins commonly cause human disease.
Tigist Bacha, Ermias Abebaw, Ayalew Moges, Amsalu Bekele, Afework Tamiru, Ishmael Shemsedin, Dawd S. Siraj, Daddi Jima, Wondwossen Amogne   +8 more
doaj   +1 more source

Clinical cases of atypical and severe botulism

Zaporožskij Medicinskij Žurnal, 2020
The aim of the work was to present two clinical cases of botulism: the atypical course and the severe course with late administration of heptavalent botulinum antitoxin, which still had a significant positive clinical effect and contributed to a faster ...
O. L. Ivakhiv, N. Yu. Vyshnevska
doaj   +1 more source

Botulism in Spain: Epidemiology and Outcomes of Antitoxin Treatment, 1997–2019

Toxins, 2022
Background: Botulism is a low incidence but potentially fatal infectious disease caused by neurotoxins produced mainly by Clostridium botulinum.
Marina Peñuelas, María Guerrero-Vadillo, Sylvia Valdezate, María Jesús Zamora, Inmaculada Leon-Gomez, Ángeles Flores-Cuéllar, Gema Carrasco, Oliva Díaz-García, Carmen Varela   +8 more
doaj   +1 more source

A systematic review of tea pigments: Prevention of major diseases, protection of organs, and potential mechanisms and applications

Food Science &Nutrition, Volume 11, Issue 11, Page 6830-6844, November 2023., 2023
Abstract With the growing awareness of a healthy life, tea pigments (TPGs) are in focus for their health benefits. TPGs not only provide specific color to tea liquor but also possess health benefits such as anti‐obesity, anti‐tumor, anti‐inflammatory, anti‐viral, anti‐oxidative, and bacteriostatic properties. Also, TPGs can benefit bone, liver, kidney,
Xuan Zhao, Fei Yan, Xin‐Sheng Li, Dong Qu, Yue‐Ling Xu   +4 more
wiley   +1 more source

Foodborne Botulism: Neglected Diagnosis

European Journal of Case Reports in Internal Medicine, 2019
Botulism is rare neuroparalytic disease caused by botulinum toxin, one of the most toxic substances known. Foodborne botulism is caused by consumption of foods contaminated with botulinum toxin.
Nuno Zarcos Palma, Mariana da Cruz, Vítor Fagundes, Lindora Pires   +3 more
doaj   +1 more source

Recombinant expression of receptor binding domains of all eight subtypes of botulinum neurotoxin type A for generation of antitoxins with broad reactivity. [PDF]

F1000Res
Quynh Pham N, Mai TT, Dang TBA, Huong Tran L, Mai Vu Q, Trong Nguyen C, Thi Phuong Tran A, Dang TNM, Tran VA, Huy Tran T, Tran VK, Quang Le H.   +11 more
europepmc   +2 more sources