Toxins, 2021 Botulism is a rare, sometimes fatal paralytic illness caused by botulinum neurotoxins. BAT® (Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)—(Equine)) is an equine-derived heptavalent botulinum antitoxin indicated for the treatment of symptomatic ...
Geraldine S. Parrera +5 more
doaj +1 more source
A pragmatic harm reduction approach to manage a large outbreak of wound botulism in people who inject drugs, Scotland 2015 [PDF]
, 2018 Background People who inject drugs (PWID) are at an increased risk of wound botulism, a potentially fatal acute paralytic illness. During the first 6 months of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland, which resulted ...
Amanda Weir +43 more
core +1 more source
A review on iatrogenic botulism
Hong Kong Journal of Emergency Medicine, Volume 27, Issue 6, Page 356-367, November 2020., 2020 Background: With the flourishing application of botulinum toxin cosmetically and therapeutically is the emergence of iatrogenic botulism, a new type of botulism in addition to the traditional ones. Objectives: We aim at a comprehensive review of the clinical characteristics of iatrogenic botulism.
Hin Tat Fung +2 more
wiley +1 more source
Clostridium botulinum – like organism bacteremia in a user of black tar heroin
IDCases, 2021 Wound botulism due to introduction of the anaerobic bacteria, Clostridium botulinum, into otherwise sterile, relatively anaerobic tissue is a known complication of black tar heroin use.
Therese Battiola +4 more
doaj
Clostridium BotulinumTypes A and B Toxin-Antitoxin Reactions [PDF]
Journal of Hygiene, 1955 SummaryC. botulinumtypes A and B toxins required larger amounts of antitoxin for neutralization when fractions of the test dose of toxin were used than would be expected.The degree of this dilution effect, i.e. the dilution ratio, varied with different sera.
openaire +3 more sources
Diverse ATPase proteins in mobilomes constitute a large potential sink for prokaryotic host ATP [PDF]
arXiv, 2021 Prokaryote mobilome genomes rely on host machineries for survival and replication. Given that mobile genetic elements (MGEs) derive their energy from host cells, we investigated the diversity of ATP-utilizing proteins in MGE genomes to determine whether they might be associated with proteins that could suppress related host proteins that consume host ...
arxiv
Modeling sRNA-regulated Plasmid Maintenance [PDF]
, 2016 We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid. Key to their function is the tight regulation of expression of a protein toxin by an sRNA antitoxin.
arxiv +1 more source
Outbreak of foodborne botulism in Alexandria, Egypt: modulating indications for administration of heptavalent botulinum antitoxin [PDF]
, 2021 Sara Attia Ghitani +4 more
+4 more sources
Wound botulism caused by Clostridium subterminale after a heroin injection
Infectious Disease Reports, 2018 Botulism is caused by toxin production from many species of Clostridium, most commonly Clostridium botulinum as well as C. baratii and C. butyricum. Development of wound botulism is associated with injection drug users but has also been described in ...
Paris A. Cook +3 more
doaj +1 more source
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]
, 1992 The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Ahnert-Hilger, G. +5 more
core +1 more source