Results 51 to 60 of about 1,891 (175)

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You   +3 more
wiley   +1 more source

A severe case of iatrogenic botulism associated with COVID-19 infection

Heliyon
Background: The botulinum toxin is an extremely potent substance that impacts the nervous system. There has been a rise in cases of medical poisoning associated with it, particularly in the field of plastic and aesthetic procedures, in recent years. Case
Qian Ma, Guang-Jing Liu, Shuang Wang, Wen-Di Wang, Ning Liu, Che-Jiang Wang, Xiao-Bing Li   +6 more
doaj   +1 more source

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash, Joseph Tam, Osnat Rosen, Hermona Soreq   +3 more
wiley   +1 more source

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on defining pathogenic strains of Shiga toxin‐producing Escherichia coli

Food Risk Assess Europe, Volume 3, Issue 3, July 2025.
ABSTRACT Shiga toxin‐producing Escherichia coli (STEC) are pathogenic E. coli strains that have been associated with a wide range of human clinical illness ranging from mild diarrhoea to bloody diarrhoea (BD) and haemolytic uremic syndrome (HUS). In its opinion of 18 May 2017, the French Agency for Food, Environmental and Occupational Health and Safety
Philippe Fravalo, Frédéric Auvray, Mickaël Boni, Frédéric Borges, Gilles Bornert, Frédéric Carlin, Catherine Chubilleau, Monika Coton, Georges Daube, Noémie Desriac, Florence Dubois‐Brissonnet, Michel Federighi, Michel Gautier, Michèle Gourmelon, Sandrine Guillou, Stéphane Guyot, Didier Hilaire, Nathalie Jourdan‐da Silva, Claire Le Henaff‐Le Marrec, Sandra Martin‐Latil, Jeanne‐Marie Membré, Eric Oswald, Nadia Oulahal, Pascal Piveteau, Sabine Schorr‐Galindo, Régine Talon, Isabelle Villena, Aurélie Cointe, Mickael Desvaux, Gabrielle Jones, Patricia Mariani‐Kurdjian, Frédérique Audiat‐Perrin, Laurent Guillier, Pauline Kooh   +33 more
wiley   +1 more source

Double Sandwich ELISA Modified Method for the Detection of Clostridium Botulinum Type E [PDF]

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: A very small amount of botulinum toxin can cause death and on the other hand, there is no cure for its poison other than antitoxin.
Mohammad Ebrahim minaei, Mojtaba Saadati
doaj   +1 more source

Studying the differential efficacy of postsymptom antitoxin treatment in type A versus type B botulism using a rabbit spirometry model

Disease Models & Mechanisms, 2018
Botulinum neurotoxin (BoNT) serotypes A, B and E are responsible for most cases of human botulism. The only approved therapy for botulism is antitoxin treatment administered to patients after symptom onset.
Amram Torgeman, Arieh Schwartz, Eran Diamant, Tzadok Baruchi, Eyal Dor, Alon Ben David, Avi Pass, Ada Barnea, Arnon Tal, Amir Rosner, Osnat Rosen, Ran Zichel   +11 more
doaj   +1 more source

Wearable Temperature Sensor Enhanced Volatilomics Technique for Swift and Convenient Detection of Latrogenic Botulism

Advanced Science, Volume 12, Issue 6, February 10, 2025.
A wearable temperature sensor enhanced volatilomics technique is developed to facilitate the rapid and convenient prediction of potential physical discomfort following botulinum neurotoxin (BoNT) injection. Through simultaneously monitoring the variation of body temperature and breath signals, this innovative strategy achieves an accuracy exceeding 91 ...
Xiaoyang Li, Yufei Yan, Chenyi Hu, Jing Wang, Jinlin Wang, Hao Yang, Daxiang Cui, Wenwen Xin, Shan Gao, Han Jin   +9 more
wiley   +1 more source

Investigating Avian Neglect and Welfare Violations: Case Studies in South Korea

Case Reports in Veterinary Medicine, Volume 2025, Issue 1, 2025.
This paper investigates three significant cases of avian welfare violations in South Korea, emphasizing the detrimental effects of neglect and inadequate management practices. The first case concerns the mass mortality of birds in a Seoul park due to methomyl poisoning. The second case focuses on a botulism outbreak occurring on a quail farm. The third
Goun Park, JaeKyeom Kim, Chunghyun Kim, Isabel Pires   +3 more
wiley   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the risk assessment of botulism resulting from the consumption of vacuum‐packed or modified atmosphere‐packed foods

Food Risk Assess Europe, Volume 3, Issue 1, January 2025.
Abstract Foodborne botulism is caused by the ingestion of a neurotoxin (BoNT) primarily produced by Clostridium botulinum. This bacterium is classified into six phenotypic Groups, with Groups I and II being associated with human disease. BoNT are divided into seven main types with different antigenic potentials, of which types A, B, E, and F are ...
María Dolores Rodrigo Aliaga, Rosa María Capita González, Baltasar Mayo Pérez, Gloria Sánchez Moragas, Antonio Valero Díaz   +4 more
wiley   +1 more source