Results 71 to 80 of about 27,210 (261)
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Analysis of Synapses in Cerebral Organoids
Cell Transplantation, 2019 Cerebral organoids are an emerging cutting-edge technology to model human brain development and neurodevelopmental disorders, for which mouse models exhibit significant limitations.
Abraam M. Yakoub, Mark Sadek
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Vascularizing the brain organoids
Journal of Molecular Cell Biology, 2022 Xin-Yao Sun, Zhen-Ge Luo
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Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
One‐Step Drug Screening System Utilizing Electrophysiological Activity in Multiple Brain Organoids
Advanced ScienceHuman‐induced pluripotent stem cell (iPSC)‐derived brain organoids have attracted significant attention as promising models for drug screening owing to their remarkable resemblance to the human brain.
Hyogeun Shin +9 more
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Human brain organoid: trends, evolution, and remaining challenges
Neural Regeneration ResearchAdvanced brain organoids provide promising platforms for deciphering the cellular and molecular processes of human neural development and diseases. Although various studies and reviews have described developments and advancements in brain organoids, few ...
Minghui Li +5 more
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Neural Regeneration Research, 2019 Multiple protocols have been devised to generate cerebral organoids that recapitulate features of the developing human brain, including the presence of a large, multi-layered, cortical-like neuronal zone.
Abraam M Yakoub
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Brain organoids and Ó?organoid intelligenceÓ�: a neuroethical critique
Bioethics UpdateBackground: The article “Brain organoids and ‘organoid intelligence’” delves into the cutting-edge research surrounding the cultivation and utilization of brain organoids. It highlights the potential of these miniaturized, simplified versions of the brain to revolutionize our understanding of neural development, disease mechanisms, and neurophysiology.
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Brain Organoid Computing -- an Overview
CoRRThe aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive bibliography covering all relevant aspects and questions on this topic. Brain organoids - three-dimensional in vitro
Yannic Talavera, Bernd Ulmann
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Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source