Results 231 to 240 of about 23,509 (295)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Building destination brands through trust: unpacking the role of digital integrated marketing communication in driving travel intentions. [PDF]

BMC Psychol
Qi M, Li J, Abdullah Z, Rahman SNA, Niu L, Zhou B, Zhao Z.   +6 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Inclusive leadership and financial-marketing decision-making in crises: gender diversity and brand resilience. [PDF]

Front Psychol
Javeed A, Khan MY, Alomair A, Al Naim AS.   +3 more
europepmc   +1 more source

The impact of perceived social support on Chinese university students' employability: a perspective based on signaling theory. [PDF]

Front Psychol
Wang G, Wang H.
europepmc   +1 more source

University marathons as structured health interventions: deconstructing the role of event culture, organization, activities and services in student engagement. [PDF]

Front Sports Act Living
Lin Y, Xie J, Jiang F, He L.
europepmc   +1 more source

Acceptability, feasibility and equity implications of nutritional supplementation interventions for the prevention of wasting in infants and young children: A rapid qualitative evidence synthesis. [PDF]

Afr J Prim Health Care Fam Med
Brand ASP, Visser ME, Kallon II, Van Wyk SSP, Rohwer AC.   +4 more
europepmc   +1 more source

Political appeals in tobacco marketing: Tucker Carlson unveils Alp nicotine pouch brand on X. [PDF]

Tob Control
Kostygina G, Carter CC, Barari S, Borowiecki M, Emery SL.   +4 more
europepmc   +1 more source