Results 101 to 110 of about 39,069 (263)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Exploring the impact of brand image and perceived value on purchasing decisions through buyer interest

open access: yesJurnal Ekonomi dan Bisnis
This study analyzes the influence of brand image and perceived value on purchasing decisions through consumer buying interest. In this context, brand image is measured by brand values, brand image, and consumer trust.
Makitta Widi Samudra   +2 more
doaj   +1 more source

The Influence of Brand Image and Brand Performance on the Brand Loyalty Uniqlo

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics (IIJSE), 2023
The objective of this research is to look into the impact of brand image and brand performance on UNIQLO brand loyalty, as well as the interaction between brand success and brand image on the development of UNIQLO brand loyalty. This research is included in the poll research category and uses questionnaires to be the research instruments. The consumers
Yudhistira, Damar Adi   +1 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Qualitative Brand Image Analysis for a Global Brand : An Intercultural Perception of the Brand Image through Brand Personality

open access: yes, 2010
The cultural differences in the consumers' perspectives are an important factor that affects the image of brands around the world. A brand's image may be affected even though the company gives the same message across different cultures. In order to analyze these effects, the authors have conducted a qualitative study, chosen the chocolate brand Kinder ...
Busch, Friederike, Planas Rego, Diego
openaire   +1 more source

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