Results 191 to 200 of about 87,953 (311)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Self-identity and consumption : a study of consumer personality, brand personality, and brand relationship [PDF]

This thesis investigates the relationship between self-identity and consumption by discussing the conceptual and measurement issues of consumer personality, brand personality, and brand relationship.
Huang, Hazel Hsiu-chen
core  

Purchase Intention of Healthy Foods: The Determinant Role of Brand Image in the Market of a Developing Country. [PDF]

Foods
García-Salirrosas EE, Escobar-Farfán M, Veas-González I, Esponda-Perez JA, Gallardo-Canales R, Ruiz-Andia R, Fernandez-Daza VM, Zabalaga-Davila RF.   +7 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The impact of brand image on customer satisfaction and brand loyalty: A systematic literature review. [PDF]

Heliyon
Tahir AH, Adnan M, Saeed Z.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Developing a sustainable nation brand: a study of Sri Lanka

, 2013
This study examines the degree to which the Earth Lung Project, a carbon mitigation initiative in Sri Lanka has developed a coherent nation brand. Findings indicate that a shared sense of national identity amongst all stakeholder groups is critical in ...
Welton, R
core  

The impact of perceived value on brand image and loyalty: a study of healthy food brands in emerging markets. [PDF]

Front Nutr
García-Salirrosas EE, Escobar-Farfán M, Esponda-Perez JA, Millones-Liza DY, Villar-Guevara M, Haro-Zea KL, Gallardo-Canales R.   +6 more
europepmc   +1 more source

Effects of Congruence between Self Image and Brand Image on Brand Attitude of Jean Brands

Journal of Korea Design Forum, 2013
null 신정란, null JinSook Hwang
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source