Results 71 to 80 of about 13,903,126 (284)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

LOYALITAS MEREK KOMUNITAS PENDAKI GUNUNG: Pengaruh Relasi Merek dan Identifikasi Komunitas dengan Mediasi Keterikatan dan Tekanan Normatif

Journal Communication Spectrum, 2018
This study is researching mountaineers’ community regarding community’s brand loyalty. With 112 samples from four mountain climbing communities in Great Jakarta, this survey measures the variables effect of Brand Relationship Quality, Community ...
Puti Rosdiana, M. Gunawan Alif
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Effect of Social Media Marketing on Consumer Behavior; Investigating the Role of Brand Equity, Brand Relationship Quality and Attitude towards Brand [PDF]

مطالعات رفتار مصرف کننده., 2018
This research aims to investigate the effect of social media marketing on consumer behavior by means of brand equity, brand relationship quality and attitude towards brand among the customers of online shops in Tehran who have followed the social media ...
Hamid Khodadad Hosseini, Niloofar Samiei, Parviz Ahmadi   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An examination of selected marketing mix elements and brand relationship quality in transition economies : evidence from Vietnam

, 2011
This study examines the role of selected marketing mix elements in brand relationship quality in a transition economy, Vietnam. A model that incorporates perceived quality, attitudes toward advertising and public relations, and brand relationship quality
Nguyen, Tho D. (R16818), Nguyen, Trang T. M., Tho D. Nguyen, Trang T. M. Nguyen   +3 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Relationships of Brand Awareness, Brand Association and Perceived Quality with Brand Loyalty and Repurchase Intention

, 2018
Due to the intense competition in market place, customers nowadays are exposed to several brands from across the globe. This study assessed the effect of brand awareness, brand association and perceived quality on brand loyalty and repurchase intention among consumers of fashion brands in Iran.
Vazifehdoost, Hossein, Azadeh Negahdari
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source