Histone post-translational modifications (PTMs) serve as an epigenetic signaling mechanism that regulates gene expression. Two of the most prevalent PTMs are acetylation, which can activate gene expression, and methylation, which can activate or repress ...
Cook, Elizabeth
core
Bioinformatic identification of genes encoding C1q-domain-containing proteins in zebrafish
C1q is the first subcomponent of classical pathway in the complement system and a major link between innate and acquired immunities. The globular (gC1q) domain similar with C1q was also found in many non-complement C1q-domain-containing (C1qDC) proteins ...
Gui, Jianfang +2 more
core
BRD proteins in human retroviral infection: emerging evidence from HIV-1 and future perspectives for HTLV-1. [PDF]
Akbarin MM, Farjami Z, Álvarez HR.
europepmc +1 more source
BRD4 binds the nucleosome via both histone and DNA interactions. [PDF]
Zhu J +7 more
europepmc +1 more source
Parasite-specific essential bromodomain protein TgBDP4 is a key epigenetic reader and a potential drug target for the parasite Toxoplasma gondii. [PDF]
Gurupwar R, Khandavalli CR, Deshmukh AS.
europepmc +1 more source
An Intact PHD Finger and PHD-BRD Interdomain Linker Are Crucial for Binding of the Chromatin Remodeler Factor TIP5 to the Histone Octamer. [PDF]
Čabart P.
europepmc +1 more source
PAX3-FOXO1 Contacts BRD4 through Its Acetylated Intrinsically Disordered Region. [PDF]
Fraser OA +3 more
europepmc +1 more source
BRD4: From molecular understanding to therapeutics development. [PDF]
Wu SY, Chiang CM.
europepmc +1 more source
Structural Genomics Defines PBRM1 Bromodomain Variant Function in ccRCC. [PDF]
Bursch KL +7 more
europepmc +1 more source
Chromatin dynamics and cellular energy homeostasis. [PDF]
Suganuma T, Workman JL.
europepmc +1 more source

