Results 121 to 130 of about 3,510,874 (207)
Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity
Plant, Cell &Environment, Volume 49, Issue 10, Page 7604-7618, October 2026.ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette +5 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 17, 14 September 2026.An investigation of the tandem Tudor domain (TTD) domain of UHRF1 identified and extensively characterized the local anesthetic hydroxyprocaine as a strong ligand capable of activating related genes such as p53 and also highlighted a new, potentially druggable intramolecular interaction between TTD and UBL.
Efstratios Tsakalidis +16 more
wiley +1 more source
, 2015 Trypanosoma brucei, the causative agent of African sleeping sickness, is transmitted to its mammalian host by the tsetse. In the fly, the parasite's surface is covered with invariant procyclin, while in the mammal it resides extracellularly in its ...
Chun-wa W. Chung +25 more
core +1 more source
Double bromodomain proteins as regulators of lymphopoiesis and inflammation
, 2012 Thesis (Ph.D.)--Boston UniversityHistone post-translational modifications are essential for the regulation of gene expression. These modifications are recognized by chromatin "readers" that control gene co-activation and co-repression through intrinsic ...
Belkina, Anna
core +1 more source
Bromodomain inhibitor treatment leads to overexpression of multiple kinases in cancer cells
Neoplasia: An International Journal for Oncology ResearchThe bromodomain and extraterminal (BET) family of proteins show altered expression across various cancers. The members of the bromodomain (BRD) family contain epigenetic reader domains that bind to acetylated lysine residues in both histone and non ...
Darshan S. Chandrashekar +7 more
doaj +1 more source
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells
Drug Design, Development and Therapy, 2018 Zhen Tan,* Xiuli Zhang,* Ting Kang, Lian Zhang, Siyu Chen Department of Oncology, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China *These authors contributed equally to this work Purpose: Gastric and colon ...
Tan Z, Zhang X, Kang T, Zhang L, Chen S
doaj