The multiple roles of C-type lectin receptors in cancer [PDF]
Frontiers in Oncology, 2023 C-type lectin receptors are a family of immune response receptors that can bind with a broad repertoire of ligands. It can function as innative immune receptors to surveillance bacteria, fungi, and virus invasions.
Qiao Li
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Mycobiota and C-Type Lectin Receptors in Cancers: Know thy Neighbors [PDF]
Frontiers in Microbiology, 2022 Numerous studies have demonstrated the importance of gut bacteria in the development of malignancy, while relatively little research has been done on gut mycobiota.
Lilong Zhang +16 more
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Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors [PDF]
Biomedicines, 2022 Neutrophil-mediated cytotoxicity toward tumor cells requires cell contact and is mediated by hydrogen peroxide. We have recently shown that Cathepsin G expressed on the neutrophil surface interacts with tumor RAGE, and this interaction facilitates ...
Ronit Vogt Sionov +2 more
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Orientia tsutsugamushi binds to multiple C-type lectin receptors [PDF]
Infection and ImmunityOrientia tsutsugamushi, the agent of scrub typhus, is an obligate intracellular bacterium whose atypical cell wall lacks many classical pathogen-associated molecular patterns but is enriched in neutral glycans.
Véronique Hefter +5 more
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From structure to function – Ligand recognition by myeloid C-type lectin receptors [PDF]
Computational and Structural Biotechnology Journal, 2022 The relevance of protein-glycan interactions in immunity has long been underestimated. Yet, the immune system possesses numerous classes of glycan-binding proteins, so-called lectins.
Swantje Fischer +3 more
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C-Type Lectin Receptors in Host Defense Against Bacterial Pathogens [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Antigen-presenting cells (APCs) are present throughout the human body—in tissues, at barrier sites and in the circulation. They are critical for processing external signals to instruct both local and systemic responses toward immune tolerance or immune ...
Malgorzata E. Mnich +4 more
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C-Type Lectin Receptors in Asthma [PDF]
Frontiers in Immunology, 2018 Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled ...
Sabelo Hadebe +5 more
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Differing Expression and Potential Immunological Role of C-Type Lectin Receptors of Two Different Chicken Breeds against Low Pathogenic H9N2 Avian Influenza Virus [PDF]
PathogensDiverse immune responses in different chicken lines can result in varying clinical consequences following avian influenza virus (AIV) infection. We compared two widely used layer breeds, Lohmann Brown (LB) and Lohmann White (LW), to examine virus ...
Sungsu Youk +2 more
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A Proposal for Nomenclature in Myeloid C-Type Lectin Receptors [PDF]
Frontiers in Immunology, 2019 Myeloid C-type lectin receptors (CLRs) comprise a family of receptors expressed by immune myeloid cells that share homologous C-type lectin domains.
Carlos del Fresno +2 more
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C-Type Lectin Receptors in Antiviral Immunity and Viral Escape [PDF]
Frontiers in Immunology, 2018 C-type lectin receptors (CLRs) are important pattern recognition receptors involved in recognition and induction of adaptive immunity to pathogens. Certain CLRs play an important role in viral infections as they efficiently interact with viruses. However,
Marta Bermejo-Jambrina +7 more
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