Soil nematode Caenorhabditis elegans Maupas as a convenient model organism to study anthelmintic activity of plant extracts [PDF]
E3S Web of Conferences, 2020 The article deals with the study of the possibility to use free-living soil nematode C. elegans in researches of anthelmintic activity of plant raw material. A. sativum juice and aqueous extract of T. vulgare flowers were used in experiments. It is shown
Egorova Anastasia +4 more
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A Pipeline for Volume Electron Microscopy of the Caenorhabditis elegans Nervous System. [PDF]
, 2018 The "connectome," a comprehensive wiring diagram of synaptic connectivity, is achieved through volume electron microscopy (vEM) analysis of an entire nervous system and all associated non-neuronal tissues. White et al.
Chisholm, Andrew D +7 more
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, 2013 To use Caenorhabditis elegans to study the mechanisms for initiation and execution of necrosis, the experimentalist should be familiar with the established models of necrosis in C. elegans and the genetic and molecular tools available. We present a summary of two contrasting models for studying necrosis in C. elegans and outline the methods for scoring
Matt, Crook +2 more
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Inappropriateness of RNAlater to preserve Caenorhabditis elegans for RNA extraction
MethodsX, 2019 Caenorhabditis elegans is a well-established laboratory animal model and has been widely used in biological research. However, it is still a challenge to obtain a good amount of quality RNA from a limited number of C. elegans for gene expression studies.
Leming Jiang +6 more
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A sterol-defined system for quantitative studies of sterol metabolism in C. elegans
STAR Protocols, 2021 Summary: This protocol describes the culturing of the nematode Caenorhabditis elegans (C. elegans) in a sterol-defined experimental system and the subsequent quantitative analysis of C.
Benjamin Trabelcy +2 more
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Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter
G3: Genes, Genomes, Genetics, 2018 Caenorhabditis elegans are typically cultured in a monoxenic medium consisting of live bacteria. However, this introduces a secondary organism to experiments, and restricts the manipulation of the nutritional environment.
Matthew R. Flavel +12 more
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Virulence behavior of uropathogenic Escherichia coli strains in the host model Caenorhabditis elegans [PDF]
, 2018 Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Although a number of bacteria can cause UTIs, most cases are due to infection by uropathogenic Escherichia coli (UPEC).
Amos +60 more
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Gap junctions in C. elegans [PDF]
Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
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The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics.
PLoS Biology, 2003 The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye.
Lincoln D Stein +35 more
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The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]
, 2010 The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page +43 more
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