Results 11 to 20 of about 57,775 (215)

Transcriptional factor PU.1 regulates decidual C1q expression in early pregnancy in human [PDF]

Frontiers in Immunology, 2015
C1q is the first recognition subcomponent of the complement classical pathway, which in addition to being synthesized in the liver, is also expressed by macrophages and dendritic cells.
Priyaa Madhukaran Raj, Uday eKishore, Kaiser eJamil, Boon eTeo, Mahesh eChoolani, Jinhua eLu   +5 more
doaj   +4 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]

, 2016
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core   +8 more sources

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination-Omicron BA.5 Infection. [PDF]

J Med Virol
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Cao J, Yang G, Cui T, Qin J, Huang D, Jin S, Yang X, Huang M, Su X, Liu S, Xia Y, Deng S, Luo C, Zhao Z, Zhang Y, Zhong N, Wang Z.   +16 more
europepmc   +2 more sources

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]

, 2015
Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C, Botto, M, Bulla, R, Durigutto, P, Guarnotta, C, Ling, GS, Rami, D, Tedesco, F, Tripodo, C, Zorzet, S   +9 more
core   +3 more sources

Complement activation and protein adsorption by carbon nanotubes [PDF]

, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel, Green, Malcolm L. H., Salvador-Morales, Carolina, Sim, Edith, Sim, Robert B., Sloan, Jeremy   +5 more
core   +2 more sources

CD93 is Selectively Expressed on Human Myeloma Cells but Not on B Lymphocytes [PDF]

Iranian Journal of Immunology, 2019
Background: CD93 has originally been known as a C1q receptor, and many studies have demonstrated that CD93 is expressed on hematopoietic stem cells, B cell progenitors, myeloid and monocytic cells.
Shohreh Fakhari, Hamed Bashiri, Bayazid Ghaderi, Kaveh Tari, Ali Jalili   +4 more
doaj   +1 more source

Factorization method for difference equations of hypergeometric type on nonuniform lattices [PDF]

, 2001
We study the factorization of the hypergeometric-type difference equation of Nikiforov and Uvarov on nonuniform lattices. An explicit form of the raising and lowering operators is derived and some relevant examples are given.Comment: 21 ...
Askey R, Atakishiyev N M, Atakishiyev N M, Atakishiyev N M, Atakishiyev N M, Atakishiyev N M, Atakishiyev N M, Bangerezako G, Biedenharn L C, Darboux G, Gasper G, Koekoek R, Lorente M, Macfarlane A J, Miller W Jr, Miller W Jr, Nagiyev Sh M, Nikiforov A F, Nikiforov A F, R S Costas-Santos, R Álvarez-Nodarse, Schrödinger E, Schrödinger E, Smirnov Yu F, Smirnov Yu F, Smirnov Yu F, Spiridonov V, Vilenkin N Ja, Álvarez-Nodarse R, Álvarez-Nodarse R, Álvarez-Nodarse R   +30 more
core   +4 more sources

A longitudinal study of C1q and anti-C1q autoantibodies in homologous and heterologous pregnancies for predicting pre-eclampsia

Frontiers in Immunology, 2022
C1q, the recognition molecule of the classical pathway of the complement system, plays a central role in pregnancy. Lack of C1q is characterized by poor trophoblast invasion and pregnancy failure.
Chiara Agostinis, Gabriella Zito, Miriam Toffoli, Isabel Peterlunger, Livia Simoni, Andrea Balduit, Erica Curtolo, Alessandro Mangogna, Beatrice Belmonte, Davide Vacca, Federico Romano, Tamara Stampalija, Tamara Stampalija, Tiziana Salviato, Federica Defendi, Nicoletta Di Simone, Nicoletta Di Simone, Uday Kishore, Giuseppe Ricci, Giuseppe Ricci, Roberta Bulla   +20 more
doaj   +1 more source

C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy [PDF]

, 2016
Introduction Guillain-Barré syndrome (GBS) is an autoimmune disease that results in acute paralysis through inflammatory attack on peripheral nerves, and currently has limited, non-specific treatment options.
Barrie, Jennifer A., Cunningham, Madeleine E., Fewou, Simon N., Furukawa, Koichi, McGonigal, Rhona, Sankaranarayanan, Sethu, Willison, Hugh J., Yao, Denggao, Yednock, Ted A.   +8 more
core   +2 more sources