Results 11 to 20 of about 51,957 (286)

Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome

open access: yesFrontiers in Immunology, 2023
Periodontal Ehlers-Danlos syndrome (pEDS) is an autosomal dominant disorder characterized by early-onset periodontitis leading to premature loss of teeth, lack of attached gingiva and thin and fragile gums leading to gingival recession. Connective tissue
Albert Amberger   +8 more
doaj   +1 more source

Identification of Diagnostic Biomarkers and Their Correlation with Immune Infiltration in Age-Related Macular Degeneration

open access: yesDiagnostics, 2021
Age-related macular degeneration (AMD) is a progressive neurodegenerative disease of the central retina, with no suitable biomarkers for early diagnosis and treatment.
Yuyang Zeng   +3 more
doaj   +1 more source

Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens.

open access: yesPLoS ONE, 2020
Several candidate HIV subunit vaccines based on recombinant envelope (Env) glycoproteins have been advanced into human clinical trials. To facilitate biopharmaceutical production, it is necessary to produce these in CHO (Chinese Hamster Ovary) cells, the
Sophia W Li   +7 more
doaj   +1 more source

An X-ray photoelectron spectroscopy study of ionic liquids based on a bridged dicationic moiety

open access: yesJournal of Chemical Research, 2022
A series of imidazolium and pyridinium-based bridged dicationic ionic liquids have been analysed using X-ray photoelectron spectroscopy. The different electronic environments of the dications have been investigated and a robust fitting model for the ...
Anham Zafar   +3 more
doaj   +1 more source

An XPS Investigation of Thermal degradation and Charring of Cross-linked Polyisoprene and Polychloroprene [PDF]

open access: yes, 2001
Our interest in butadiene-containing polymers had led to an investigation of the thermal degradation of polyisoprene, PIP, and polychloroprene, PCP. The connection between cross-linking and thermal stability through an examination of PIP and PCP has been
Hao, JIanwei   +2 more
core   +2 more sources

Molecular double core-hole electron spectroscopy for chemical analysis [PDF]

open access: yes, 2010
We explore the potential of double core hole electron spectroscopy for chemical analysis in terms of x-ray two-photon photoelectron spectroscopy (XTPPS).
Christian Buth   +8 more
core   +1 more source

Niemann-Pick C1 [PDF]

open access: yesCurrent Biology, 2002
What is it? Niemann-Pick C1 (NPC1) is a 1278 amino acid membrane protein residing in the endosomal–lysosomal system. Studies in humans and animal models substantiate NPC1 as a crucial player in intracellular cholesterol trafficking.Can we live without it?
Liscum, Laura, Wojtanik, Kari
openaire   +2 more sources

Construction of a competitive endogenous RNA network and analysis of potential regulatory axis targets in glioblastoma

open access: yesCancer Cell International, 2021
Background Glioblastoma is the most common primary malignant brain tumor. Because of the limited understanding of its pathogenesis, the prognosis of glioblastoma remains poor. This study was conducted to explore potential competing endogenous RNA (ceRNA)
Kai Yu   +11 more
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

open access: yes, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H.   +4 more
core   +1 more source

C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency

open access: yesOrphanet Journal of Rare Diseases, 2023
Abstract Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods.
Zsofia Polai   +6 more
openaire   +3 more sources

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