Results 191 to 200 of about 6,618 (201)

Targeting C5aR1 Reveals Protective Macrophage Maturation States in Intestinal Injury

Abstract Inflammatory intestinal injury, which may occur following cytotoxic cancer treatments such as radiotherapy, compromises homeostasis when intestinal stem cells undergo apoptosis and regeneration programmes are not effectively engaged.
Heather Clark, Ian J. Chai, Stavros Melemenidis, Dhanya K. Nambiar, Kim K. Ryan, Yanyan Jiang, Kerriann M. Casey, Iryna Zherka, Dominika Majorova, Trent M. Woodruff, Edward G. Graves, Quynh-Thu Le, Simon JA. Buczacki, Amato J. Giaccia, Monica M. Olcina   +14 more
openaire   +1 more source

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Nature, 2020
Julien Carvelli, Boris Pastorino, Christophe Guervilly   +2 more
exaly  

C5aR1 promotes the progression of colorectal cancer by EMT and activating Wnt/β-catenin pathway

Clinical and Translational Oncology, 2022
Tao Yin, Xingwang Sun
exaly  

Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function

Biochemical Pharmacology, 2020
Xaria X Li, John D Lee, Avril A B Robertson   +2 more
exaly  

Loss of C5aR1 in Foxd1+ stromal cells reduces kidney fibrosis

Molecular Immunology, 2018
Ranjit Sahu, Sandhya Xavier, Ronald Taylor, William Stallcup, Jörg Köhl, Didier Portilla   +5 more
openaire   +1 more source

The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury

Kidney International, 2019
Qi Peng, Bo Cao, Ke Li
exaly  

Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways

Brain, Behavior, and Immunity, 2017
Fei Ding, Cai Ping Wang
exaly  

C3aR and C5aR1 act as key regulators of human and mouse β-cell function

Cellular and Molecular Life Sciences, 2017
Patricio Atanes, Inmaculada Ruz-Maldonado, Attilio Pingitore   +2 more
exaly  

Elucidating the role of neuronal C5aR1

openaire   +1 more source

C5a-C5aR1 axis controls mitochondrial fission to promote podocyte injury in lupus nephritis

Molecular Therapy
Mianjing, Yuefang Huang, Niansheng Yang
exaly