Results 1 to 10 of about 321,674 (333)
Toxins, 2022 Transgenic crops producing Bacillus thuringiensis (Bt) insecticidal proteins are grown widely for pest control, but the evolution of resistance in target pests could reduce their efficacy.
Shan Yu +5 more
doaj +1 more source
Interplay of Eph-Ephrin Signalling and Cadherin Function in Cell Segregation and Boundary Formation
Frontiers in Cell and Developmental Biology, 2021 The segregation of distinct cell populations to form sharp boundaries is crucial for stabilising tissue organisation, for example during hindbrain segmentation in craniofacial development.
David G. Wilkinson
doaj +1 more source
Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes
Frontiers in Cell and Developmental Biology, 2022 Background: The mechanism of tumorigenicity potentially evolved in mesenchymal stem cells (MSCs) remains elusive, resulting in inconsistent clinical application efficacy.
Andres Stucky +16 more
doaj +1 more source
Mutation in the Cadherin Gene Is a Key Factor for Pink Bollworm Resistance to Bt Cotton in China
Toxins, 2022 Transgenic crops producing Bacillus thuringiensis (Bt) toxins are widely planted for insect control, but their efficacy may decrease as insects evolve resistance.
Ling Wang +8 more
doaj +1 more source
Journal of Cell Science, 2008 The cadherin molecules at adherens junctions have multiple isoforms. Cadherin isoform switching (cadherin switching) occurs during normal developmental processes to allow cell types to segregate from one another. Tumor cells often recapitulate this activity and the result is an aggressive tumor cell that gains the ability to leave the site of the tumor
Margaret J, Wheelock +4 more
openaire +2 more sources
Autoregulation of E-cadherin expression by cadherin–cadherin interactions [PDF]
The Journal of Cell Biology, 2003 Transcriptional repression of E-cadherin, characteristic of epithelial to mesenchymal transition, is often found also during tumor cell invasion. At metastases, migratory fibroblasts sometimes revert to an epithelial phenotype, by a process involving regulation of the E-cadherin–β-catenin complex. We investigated the molecular basis of this regulation,
Maralice Conacci-Sorrell +5 more
openaire +1 more source
eLife, 2021 Morphogenesis is governed by the interplay of molecular signals and mechanical forces across multiple length scales. The last decade has seen tremendous advances in our understanding of the dynamics of protein localization and turnover at subcellular ...
Robert J Huebner +5 more
doaj +1 more source
Cell Adhesion Molecules in Neuroblastoma: Complex Roles, Therapeutic Potential
Frontiers in Oncology, 2022 Neuroblastoma, a biologically heterogeneous tumor derived from neural crest cells, accounts for approximately 15% of childhood deaths from cancer.
Briana E. Heinly +2 more
doaj +1 more source
Mutations in a Novel Cadherin Gene Associated with Bt Resistance in Helicoverpa zea
G3: Genes, Genomes, Genetics, 2020 Transgenic corn and cotton produce crystalline (Cry) proteins derived from the soil bacterium Bacillus thuringiensis (Bt) that are toxic to lepidopteran larvae. Helicoverpa zea, a key pest of corn and cotton in the U.S., has evolved widespread resistance
Megan L. Fritz +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles ...
Aoqi Li +3 more
doaj +1 more source