Results 61 to 70 of about 25,936 (261)
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Circulating cell adhesion molecules in systemic sclerosis: a systematic review and meta-analysis
Frontiers in ImmunologyIntroductionPatients with systemic sclerosis (SSc) have an increased risk of endothelial dysfunction, atherosclerosis, and cardiovascular events compared to the general population.
Arduino A. Mangoni +2 more
doaj +1 more source
Top2b regulates morphological and migratory properties of retinal progenitor cells in vivo and upon transplantable matrix substrates [PDF]
Exploration of BioMat-XAim: This study evaluated the impact of retinal extracellular matrix (ECM) and key biomaterial substrates on the motility of transplantable retinal cells with genomic manipulation, using the therapeutic molecule, Topoisomerase II beta (Top2b), as a model.
Alexandra C. Dabrowski +5 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi +5 more
wiley +1 more source
Biophysical Tools to Study Cellular Mechanotransduction
Bioengineering, 2017 The cell membrane is the interface that volumetrically isolates cellular components from the cell’s environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane ...
Ismaeel Muhamed +2 more
doaj +1 more source
Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
Advanced Functional Materials, EarlyView.In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni +8 more
wiley +1 more source
Evaluation of CDH1;RUNX3 Expression in Cancerous and Normal Tissue of Patients With Gastric Cancer
پزشکی بالینی ابن سینا, 2017 Introduction: Gastric cancer is a multifactorial disease and the fourth most common cancer in the world and the second cause of death from cancer. This study was designed and performed to investigate CDH1 and RUNX3 genes expression in healthy and tumor ...
M Einolghozati +4 more
doaj
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2018 While the numerous influences of synaptically released zinc on synaptic efficiency during long-term potentiation have been discussed by many authors already, we focused on the possible effect of zinc on cadherins and therefore its contribution to ...
Christoph Wolf +4 more
doaj +1 more source