Results 21 to 30 of about 584 (117)

International consensus statement on allergy and rhinology: Allergic rhinitis – 2023

open access: yesInternational Forum of Allergy &Rhinology, Volume 13, Issue 4, Page 293-859, April 2023., 2023
Abstract Background In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR‐Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40
Sarah K. Wise   +126 more
wiley   +1 more source

Key Considerations for the Development of Safe and Effective SARS‐CoV‐2 Subunit Vaccine: A Peptide‐Based Vaccine Alternative

open access: yesAdvanced Science, Volume 8, Issue 16, August 18, 2021., 2021
Careful antigen selection is essential for development of an effective and safe SARS‐CoV‐2 vaccine. Considering recent advances, peptide vaccines can be ideal substitutes for protein and RNA/DNA‐based vaccines. Peptide vaccines can avoid immunopathological sequences, focus immune responses on neutralizing B‐cell and on T‐cell epitopes, combine antigens
Ahmed O. Shalash   +3 more
wiley   +1 more source

Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate

open access: yesVeterinary Research, 2020
Conserved epitopes are targets commonly researched to be part of universal vaccine candidates against influenza viruses (IV). These conserved epitopes need to be cross-protecting against distinct IV subtypes and to have a strong immunogenic potential ...
Marta Sisteré-Oró   +5 more
doaj   +1 more source

Injection Vaccines Formulated with Nucleotide, Liposomal or Mineral Oil Adjuvants Induce Distinct Differences in Immunogenicity in Rainbow Trout

open access: yesVaccines, 2020
Protection facilitated by the widespread use of mineral oil adjuvanted injection vaccines in salmonid fish comes with adverse effects of varying severity. In this study, we characterized the immunological profiles of two alternative vaccine formulations,
Kasper Rømer Villumsen   +4 more
doaj   +1 more source

Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: It is now emerging that for vaccines against a range of diseases including influenza, malaria and HIV, the induction of a humoral response is insufficient and a substantial complementary cell-mediated immune response is necessary for adequate
Else Marie Agger   +12 more
doaj   +1 more source

A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: In the search for more potent and safer tuberculosis vaccines, CAF01 was identified as a remarkable formulation. Based on cationic liposomes and including a synthetic mycobacterial glycolipid as TLR-independent immunomodulator, it induces ...
Arun T Kamath   +6 more
doaj   +1 more source

A novel liposome-based adjuvant CAF01 for induction of CD8(+) cytotoxic T-lymphocytes (CTL) to HIV-1 minimal CTL peptides in HLA-A*0201 transgenic mice. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Specific cellular cytotoxic immune responses (CTL) are important in combating viral diseases and a highly desirable feature in the development of targeted HIV vaccines. Adjuvants are key components in vaccines and may assist the HIV immunogens
Gregers Jacob Gram   +4 more
doaj   +1 more source

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System

open access: yesFrontiers in Immunology, 2018
The induction and modulation of the immune response to vaccination can be rationally designed by combining different vaccine formulations for priming and boosting.
Annalisa Ciabattini   +10 more
doaj   +1 more source

Therapeutic Vaccination with Cationic Liposomes Formulated with Dioctadecyldimethylammonium and Trehalose Dibehenate (CAF01) and Peptide P10 Is Protective in Mice Infected with Paracoccidioides brasiliensis

open access: yesJournal of Fungi, 2020
The peptide P10 is a vaccine candidate for Paracoccidioidomycosis, a systemic mycosis caused by fungal species of the genus Paracoccidioides spp. We have previously shown that peptide P10 vaccination, in the presence of several different adjuvants ...
Marcelo Valdemir de Araújo   +3 more
doaj   +1 more source

Computational Analysis of Multiparametric Flow Cytometric Data to Dissect B Cell Subsets in Vaccine Studies

open access: yesCytometry Part A, Volume 97, Issue 3, Page 259-267, March 2020., 2020
The generation of the B cell response upon vaccination is characterized by the induction of different functional and phenotypic subpopulations and is strongly dependent on the vaccine formulation, including the adjuvant used. Here, we have profiled the different B cell subsets elicited upon vaccination, using machine learning methods for interpreting ...
Simone Lucchesi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy