Results 31 to 40 of about 3,141 (147)
Yersinia pestis caf1Variants and the Limits of Plague Vaccine Protection [PDF]
Infection and Immunity, 2008 ABSTRACTYersinia pestis, the highly virulent agent of plague, is a biological weapon. Strategies that prevent plague have been sought for centuries, and immunization with live, attenuated (nonpigmented) strains or subunit vaccines with F1 (Caf1) antigen is considered effective.
Lauriane E, Quenee +4 more
openaire +2 more sources
Molecular Plant-Microbe Interactions, 2014 To decipher the mechanism of pathogenicity in Sclerotinia sclerotiorum, a pathogenicity-defective mutant, Sunf-MT6, was isolated from a T-DNA insertional library.
Xueqiong Xiao +6 more
doaj +1 more source
Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation [PDF]
Molecular Cell, 2009 MicroRNAs (miRNAs) inhibit mRNA expression in general by base pairing to the 3'UTR of target mRNAs and consequently inhibiting translation and/or initiating poly(A) tail deadenylation and mRNA destabilization. Here we examine the mechanism and kinetics of miRNA-mediated deadenylation in mouse Krebs-2 ascites extract.
Fabian, Marc R +16 more
openaire +4 more sources
BMC Microbiology, 2019 Background Thermal regulation of gene expression occurs in many microorganisms, and is mediated via several typical mechanisms. Yersinia pestis is the causative agent of the plague and spreads by zoonotic transfer from fleas to mammalian blood with a ...
Abdulmajeed D. Al-Jawdah +5 more
doaj +1 more source
Unraveling the molecular determinants of the anti-phagocytic protein cloak of plague bacteria.
PLoS Pathogens, 2022 The pathogenic bacterium Yersina pestis is protected from macrophage engulfment by a capsule like antigen, F1, formed of long polymers of the monomer protein, Caf1.
Daniel T Peters +7 more
doaj +1 more source
Thermal stability and rheological properties of the ‘non-stick’ Caf1 biomaterial
Biomedical Materials, 2017 The ability to culture cells in three-dimensions has many applications, from drug discovery to wound healing. 3D cell culture methods often require appropriate scaffolds that mimic the cellular environments of different tissue types. The choice of material from which these scaffolds are made is of paramount importance, as its properties will define the
Ulusu Y +6 more
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Anti‐proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase [PDF]
The EMBO Journal, 2011 Tob is a member of the anti-proliferative protein family, which functions in transcription and mRNA decay. We have previously demonstrated that Tob is involved in the general mechanism of mRNA decay by mediating mRNA deadenylation through interaction with Caf1 and a general RNA-binding protein, PABPC1.
Nao, Hosoda +8 more
openaire +2 more sources
PTCDA adsorption on CaF2 thin films
Beilstein Journal of Nanotechnology, 2020 Thin insulating films are commonly employed for the electronic decoupling of molecules as they enable a preservation of the intrinsic molecular electronic functionality.
Philipp Rahe
doaj +1 more source
Engineered mosaic protein polymers; a simple route to multifunctional biomaterials
Journal of Biological Engineering, 2019 Background Engineered living materials (ELMs) are an exciting new frontier, where living organisms create highly functional materials. In particular, protein ELMs have the advantage that their properties can be manipulated via simple molecular biology ...
Daniel T. Peters +3 more
doaj +1 more source
СAPSULAR ANTIGEN OF YERSINIA PESTIS
Инфекция и иммунитет, 2015 Plague is a zoonosis caused by gram-negative bacteria Yersinia pestis, which, as a rule, is transmitted to humans from septicemic rodents by the bites of infected fleas. This microbe killed more people than all of the wars in the human history. Y. pestis
L. A. Kadnikova +3 more
doaj +1 more source