Results 81 to 90 of about 3,141 (147)
Design of Multiplex Polymerase Chain Reaction (PCR) Method for Molecular Detection of Yersinia pestis Bacterium [PDF]
Cell Journal, 2010 Objective: Yersinia pestis, the causative agent of the zoonotic plague infection, is a majorpublic health concern both as a threat and potential bioweapon.
Mohammad Soleimani +7 more
doaj
PLoS Pathogens, 2019 With relatively few known specific transcription factors to control the abundance of specific mRNAs, Plasmodium parasites may rely more on the regulation of transcript stability and turnover to provide sufficient gene regulation.
Kevin J Hart +7 more
doaj +1 more source
Molecular Detection and Genotyping of Enterocytozoon bieneusi in Racehorses in China
Frontiers in Microbiology, 2019 Enterocytozoon bieneusi is a widely distributed human and animal pathogen. However, few data are available on the distribution of E. bieneusi genotypes in racehorses.
Aiyun Zhao +7 more
doaj +1 more source
Evaluation of immunohistochemical expression of ghrelin-producing rectal cells in Wistar rats underwent to the cafeteria diet [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE:To investigate the impact of cafeteria diet on ghrelin expression in rectal tissue and identify the morphologic cell type. METHODS:Twenty-four male Wistar rats were divided into four subgroups of six animals each: RC1 (rat chow 1) and CAF1 ...
Humberto Fenner Lyra Junior +7 more
doaj +1 more source
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila [PDF]
The EMBO Journal, 2004 The CCR4-NOT complex is the major enzyme catalyzing mRNA deadenylation in Saccharomyces cerevisiae. We have identified homologs for almost all subunits of this complex in the Drosophila genome. Biochemical fractionation showed that the two likely catalytic subunits, CCR4 and CAF1, were associated with each other and with a poly(A)-specific 3 ...
Claudia, Temme +4 more
openaire +2 more sources
Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity [PDF]
Nucleic Acids Research, 2008 BTG2 is the prototypical member of the TOB family and is known to be involved in cell growth, differentiation and DNA repair. As a transcriptional co-regulator, BTG2 interacts with CCR4-associated factor 1 (CAF1) and POP2 (CALIF), which are key components of the general CCR4/NOT multi-subunit transcription complex, and which are reported to play ...
Yang, Xiuna +10 more
openaire +2 more sources
Molecular subtyping and precision therapy for esophageal cancer
Interdisciplinary Medicine, Volume 3, Issue 3, May 2025.The molecular typing of esophageal cancer based on genome, transcriptome, proteome, and multi‐omics revealed various molecular features and provided potential targets for the precision therapy. Recent trials have shown that immunotherapy or molecular targeted therapy plus chemoradiotherapy can improve overall survival and progression‐free survival in ...
Guangkun Pei +5 more
wiley +1 more source
Journal of Extracellular Biology, Volume 4, Issue 3, March 2025.ABSTRACT Several reports have demonstrated that CD147, an N‐glycosylated protein that is exchanged by cells in soluble form or through small extracellular vesicles (sEVs), can promote cancer progression. However, its activity related to EVs in colorectal cancer (CRC) is still not fully understood.
Filomena Colella +15 more
wiley +1 more source
Engineering Lipid Nanoparticles for mRNA Immunotherapy
WIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 2, March/April 2025.ABSTRACT Over the last decades, messenger RNA (mRNA) has emerged as a promising therapeutic modality, enabling the delivery of genetic instructions to cells for producing therapeutic proteins or antigens. As such, mRNA‐based therapies can be developed for a wide range of conditions, including infections, cancer, metabolic disorders, and genetic ...
Robby Zwolsman +3 more
wiley +1 more source
Synthesis and expression of caf1 gene encoding F1 antigen of Yersinia pestis
Vietnam Journal of Biotechnology, 2016 Yersinia pestis is the etiologic agent of plague, one of the most deadly infectious diseases described in the history of humanity. It was responsible for millions of deaths all over the world. Yersinia pestis also can be used as a highly lethal biological potential weapon. For plague diagnosis in humans as well as to detect Y. pestis in the environment,
Nguyễn Thị Thu Hà +4 more
openaire +2 more sources