Results 141 to 150 of about 12,490 (282)

First Insights Into the LC‐HRMS Profiling and Biological Activities of Crocus graveolens

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This study reports the first comprehensive analysis of Crocus graveolens Boiss. & Reut. using LC‐HRMS, identifying 33 secondary metabolites, with rutin as the major compound (162.808 ± 4.5 μg/g extract). The extract showed moderate antioxidant activity and effectively inhibited acetylcholinesterase (30.88% ± 1.51%) and butyrylcholinesterase (61.22% ± 0.
Ezgi Ersoy, Mehmet Boğa, Alevcan Kaplan, Emel Mataracı Kara, Serpil Demirci Kayıran, Esra Eroğlu Özkan   +5 more
wiley   +1 more source

Protective Effects of Caffeic Acid Phenethyl Ester Against Carbon Tetrachloride-induced Testicular Damage in Rats: A Histological Study

, 2023
Belemir Gülhan, Elif Taşlıdere, Nigar Vardı, Aslı Çetin, Hülya Elbe   +4 more
openalex   +1 more source

Caffeic Acid Phenethyl Ester and Ethanol Extract of Propolis Induce the Complementary Cytotoxic Effect on Triple-Negative Breast Cancer Cell Lines

Molecules, 2015
Chemotherapy of breast cancer could be improved by bioactive natural substances, which may potentially sensitize the carcinoma cells’ susceptibility to drugs. Numerous phytochemicals, including propolis, have been reported to interfere with the viability
Anna Rzepecka-Stojko, Agata Kabała-Dzik, Aleksandra Moździerz, Robert Kubina, Robert D. Wojtyczka, Rafał Stojko, Arkadiusz Dziedzic, Żaneta Jastrzębska-Stojko, Magdalena Jurzak, Ewa Buszman, Jerzy Stojko   +10 more
doaj   +1 more source

Flavonoids and sugar disease [PDF]

, 2009
Diabetes melliuts je metabolički i hormonalni poremećaj za koji je karakteristična trajna hiperglikemija. Nastaje kao rezultat nedovoljnog izlučivanja hormona inzulina, nedovoljnog odgovora ciljnih stanica na inzulin, ili kombinacije ovih dvaju faktora ...
Janković, Iva
core   +2 more sources

NADH autofluorescence, a new metabolic biomarker for cancer stem cells : identification of Vitamin C and CAPE as natural products targeting “stemness” [PDF]

, 2017
Here, we assembled a broad molecular “tool-kit” to interrogate the role of metabolic heterogeneity in the propagation of cancer stem-like cells (CSCs).
Abramov, Bottiroli, Cantley, Clarke, Dang, Duchen, Goliaei, Gratton, He, Heeschen, Inoue, Kuo, Kyprianou, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Lisanti, Menendez, Nygren, Pauling, Pestell, Scheinberg, Shu, Sotgia, Sotgia, Tragoolpua, Wanibuchi, Wicha, Wicha, Wolk   +33 more
core   +1 more source

New Caffeic Acid Phenylethyl Ester Analogs Bearing Substituted Triazole: Synthesis and Structure-Activity Relationship Study towards 5-Lipoxygenase Inhibition

Journal of Chemistry, 2017
Leukotrienes are biosynthesized by the conversion of arachidonic acid by 5-Lipoxygenase and play a key role in many inflammatory disorders. Inspired by caffeic acid phenylethyl ester (CAPE) (2) and an analog carrying a triazole substituted by cinnamoyl ...
Pierre-Philipe Roy, Diene Faye, Sébastien Blanchard, Marc Cormier, Jérémie A. Doiron, Marc E. Surette, Mohamed Touaibia   +6 more
doaj   +1 more source

Protective role of caffeic acid phenethyl ester against tetramethrine-induced toxicity in mice

Medicine Science, 2016
The purpose of this study was to determine the biochemical, histopathological and genotoxic effects of tetramethrine, which is widely used in domestic and agricultural activities as well as identify the protective effect of caffeic acid phenethyl ester (
Gokhan Nur, Haci Ahmet Deveci, Yusuf Ersan, Oguz Merhan, Mumtaz Nazli, Ozlem Nur   +5 more
doaj   +1 more source

Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease [PDF]

, 2019
The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs.
Antonella Amato, Flavia Mulè, Simona Terzo   +2 more
core   +1 more source

The neuroprotective effects of caffeic acid phenethyl ester against methamphetamine-induced neurotoxicity

Ecotoxicology and Environmental Safety
Methamphetamine (METH) is a highly abused substance on a global scale and has the capacity to elicit toxicity within the central nervous system. The neurotoxicity induced by METH encompasses neuronal degeneration and cellular demise within the substantia
Bin Yang, Xiaohui Tan, Yuzhen Chen, Jing Lin, Jingjie Liang, Xia Yue, Dongfang Qiao, Huijun Wang, Sihao Du   +8 more
doaj   +1 more source

Efficacy of vitamin E in the conservative treatment of Peyronie's disease: legend or reality? A controlled study of 70 cases [PDF]

, 2013
The medical treatment is indicated in the development stage of Peyronie’s disease (PD) for at least 1 year after diagnosis and whenever in case of penile pain.
Alvaro, R, Brancato, T, D'Ascenzo, R, De Giorgio, G, Nupieri, P, Orsolini, G, Paulis, G   +6 more
core   +1 more source